Parcourir Faculté de pharmacie – Travaux et publications par auteur·e "Holtz, Timothy H."
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Causal inference with multiple concurrent medications: a comparison of methods and an application in multidrug-resistant tuberculosis
Siddique, Arman Alam; Schnitzer, Mireille; Bahamyirou, Asma; Guanbo, Wang; Holtz, Timothy H.; Migliori, Giovanni B (SAGE, 2018-10-31)This paper investigates different approaches for causal estimation under multiple concurrent medications. Our parameter of interest is the marginal mean counterfactual outcome under different combinations of medications. We explore parametric and ... -
Estimating treatment importance in multidrug-resistant tuberculosis using Targeted Learning : an observational individual patient data network meta-analysis
Estimating MDR-TB treatment importance using TMLE
Wang, Guanbo; Schnitzer, Mireille; Menzies, Dick; Viiklepp, Piret; Holtz, Timothy H.; Benedetti, Andrea (Wiley, 2019)Persons with multidrug‐resistant tuberculosis (MDR‐TB) have a disease resulting from a strain of tuberculosis (TB) that does not respond to at least isoniazid and rifampicin, the two most effective anti‐TB drugs. MDR‐TB is always treated with multiple ...