Now showing items 1-2 of 2

  • Nanonization of megestrol acetate by laser fragmentation in aqueous milieu 

    Sylvestre, Jean-Philippe; Tang, Marie-Christine; Furtos, Alexandra; Leclair, Grégoire; Meunier, Michel; Leroux, Jean-Christophe (2011-02-10)
    Nanonization is a simple and effective method to improve dissolution rate and oral bioavailability of drugs with poor water solubility. There is growing interest to downscale the nanocrystal production to enable early preclinical evaluation of new ...
  • Tyrosine-based rivastigmine-loaded organogels in the treatmant of Alzheimer's disease 

    Bastiat, Guillaume; Plourde, François; Motulsky, Aude; Furtos, Alexandra; Dumont, Yvan; Quirion, Rémi; Fuhrmann, Gregor; Leroux, Jean-Christophe (2010-08)
    Organogels can be prepared by immobilizing an organic phase into a threedimensional network coming from the self-assembly of a low molecular weight gelator molecule. In this work, an injectable subcutaneous organogel system based on safflower oil and ...