Now showing items 1-4 of 4

  • Biomarkers of dementia in obstructive sleep apnea 

    Baril, Andrée-Ann; Carrier, Julie; Lafrenière, Alexandre; Warby, Simon; Poirier, Judes; Osorio, Ricardo S.; Ayas, Najib; Dubé, Marie-Pierre; Petit, Dominique; Gosselin, Nadia; Canadian Sleep and Circadian Network (Elsevier, 2018-08-13)
    Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due to obstructive sleep apnea may significantly ...
  • Cerebral white matter diffusion properties and free‐water with obstructive sleep apnea severity in older adults 

    Baril, Andrée‐Ann; Gagnon, Katia; Descoteaux, Maxime; Bedetti, Christophe; Chami, Sirin; Sanchez, Erlan; Montplaisir, Jacques-Yves; De Beaumont, Louis; Gilbert, Danielle; Poirier, Judes; Pelleieux, Sandra; Osorio, Ricardo S.; Carrier, Julie; Gosselin, Nadia (Wiley, 2020-03-13)
    Characterizing the effects of obstructive sleep apnea (OSA) on the aging brain could be key in our understanding of neurodegeneration in this population. Our objective was to assess white matter properties in newly diagnosed and untreated adults with ...
  • Obstructive sleep apnea and the risk of cognitive decline in older adults 

    Gosselin, Nadia; Baril, Andrée-Ann; Osorio, Ricardo S.; Kaminska, Marta; Carrier, Julie (American Thoracic Society, 2019-01-15)
    Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure and function. Recent cohort ...
  • Sleep oscillation-specific associations with Alzheimer’s disease CSF biomarkers : novel roles for sleep spindles and tau 

    Kam, Korey; Parekh, Ankit; Sharma, Ram A.; Andrade, Andreia; Lewin, Monica; Castillo, Bresne; Bubu, Omonigho M.; Chua, Nicholas J.; Miller, Margo D.; Mullins, Anna E.; Glodzik, Lidia; Mosconi, Lisa; Gosselin, Nadia; Prathamesh, Kulkarni; Chen, Zhe; Blennow, Kaj; Zetterberg, Henrik; Bagchi, Nisha; Cavedoni, Bianca; Rapoport, David M.; Ayappa, Indu; De Leon, Mony J.; Petkova, Eva; Varga, Andrew W.; Osorio, Ricardo S. (BMC, 2019-02-21)
    Background: Based on associations between sleep spindles, cognition, and sleep-dependent memory processing, here we evaluated potential relationships between levels of CSF Aβ42, P-tau, and T-tau with sleep spindle density and other biophysical ...