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Now showing items 21-27 of 27
Increased platelet reactivity and platelet–leukocyte aggregation after elective coronary bypass surgery
(Taylor & Francis, 2018-11-13)
Inflammatory mechanisms are activated, and thrombotic complications occur during the initial
months after coronary artery bypass grafting (CABG). Therefore, changes over time of platelet
activation and platelet–leukocyte ...
Clinical importance of thrombocytopenia in patients with acute coronary syndromes : a systematic review and meta-analysis
Thrombocytopenia in acute coronary syndromes
(Taylor & Francis, 2018-10-22)
Thrombocytopenia (TP) is common in hospitalized patients. In the context of acute coronary syndromes (ACS), TP has been linked to adverse clinical outcomes. We present a systematic review and meta-analysis of the evidence ...
Antiplatelet therapy for atherothrombotic disease in 2022 : from population to patient-centered approaches
(Frontiers Media, 2022-01-28)
Antiplatelet agents, with aspirin and P2Y12 receptor antagonists as major key molecules, are currently the cornerstone of pharmacological treatment of atherothrombotic events including a variety of cardio- and cerebro-vascular ...
Clinical correlates identify ProBDNF and thrombo-inflammatory markers as key predictors of circulating p75NTR extracellular domain levels in older adults
(Frontiers Media, 2022-02-21)
The p75NTR receptor binds all neurotrophins and is mostly known for its role in neuronal survival and apoptosis. Recently, the extracellular domain (ECD) of p75NTR has been reported in plasma, its levels being dysregulated ...
Head‐to‐Head comparison of consensus‐recommended platelet function tests to assess P2Y12 Inhibition : insights for multi‐center trials
(MDPI, 2020)
The vasodilator‐associated stimulated phosphoprotein (VASP) phosphorylation level is a
highly specific method to assess P2Y12 receptor inhibition. Traditionally, VASP phosphorylation is
analyzed by flow cytometry, which ...
Study of the bioaccumulation of tinzaparin in renally impaired patients when given at prophylactic doses : The STRIP study
Prophylactic tinzaparin in severe renal disease
(Elsevier, 2018-12-02)
Platelet function tests
(Thieme Publishing, 2016-04)
Traditionally developed for diagnosis of bleeding disorders, platelet function assays have
become increasingly used in basic research on platelet physiology, in phenotype-genotype
associations in bleeding disorders, in ...