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High prevalence of SARS-CoV-2 antibodies and low prevalence of SARS-CoV-2 RNA in cats recently exposed to human cases
(BMC, 2024-07-09)Background The primary objective of this cross-sectional study, conducted in Québec and Bristish Columbia (Canada) between February 2021 and January 2022, was to measure the prevalence of viral RNA in oronasal and rectal swabs and serum antibodies to ... -
Host immune response modulation in avian coronavirus infection : tracheal transcriptome profiling in vitro and in vivo
(MDPI, 2024-04-14)Infectious bronchitis virus (IBV) is a highly contagious Gammacoronavirus causing moderate to severe respiratory infection in chickens. Understanding the initial antiviral response in the respiratory mucosa is crucial for controlling viral spread. We ... -
Anandamide modulates thermal avoidance in caenorhabditis elegans through vanilloid and cannabinoid receptor interplay
(Springer, 2024-03-27)Understanding the endocannabinoid system in C. elegans may offer insights into basic biological processes and potential therapeutic targets for managing pain and inflammation in human. It is well established that anandamide modulates pain perception ... -
DUSP1 mRNA modulation during porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus co-infection regulates viruses replication
(Elsevier, 2023-12-01)The effects of porcine circovirus type 2b (PCV2b) and porcine reproductive and respiratory syndrome virus (PRRSV) co-infection in epithelial cells of the swine respiratory tract is unknown. In the present study, the newborn pig trachea cell line ... -
Cannabidiol and tetrahydrocannabinol antinociceptive activity is mediated by distinct receptors in caenorhabditis elegans
(Springer, 2023-11-22)Cannabis has gained popularity in recent years as a substitute treatment for pain following the risks of typical treatments uncovered by the opioid crisis. The active ingredients frequently associated with pain-relieving effects are the phytocannabinoids ... -
Cannflavins isolated from cannabis sativa impede caenorhabditis elegans response to noxious heat
(Springer, 2023-07-22)Cannflavins, flavonoids abundantly present in Cannabis sativa, possess a distinct chemical structure comprising a vanillyl group. Notably, the capsaicin structure also contains a vanillyl group, which is considered essential for interacting with the ... -
Porcine circovirus modulates swine influenza virus replication in pig tracheal epithelial cells and porcine alveolar macrophages
(MDPI, 2023-05-20)The pathogenesis of porcine circovirus type 2b (PCV2b) and swine influenza A virus (SwIV) during co-infection in swine respiratory cells is poorly understood. To elucidate the impact of PCV2b/SwIV co-infection, newborn porcine tracheal epithelial ... -
Establishment of preliminary reference intervals and cytochemical staining of blood cells in big-bellied seahorses (Hippocampus abdominalis)
(Wiley, 2023-03-10)AbstractBackground: Despite their popularity, hematology reference intervals (RIs) have not been established in big- bellied seahorses (Hippocampus abdominalis).Objective: The objectives of this study were to establish hematologic RIs to compare values ... -
Antinociceptive activity of vanilloids in caenorhabditis elegans is mediated by the desensitization of the TRPV channel OCR-2 and specific signal transduction pathways
(Springer, 2023-02-03)Vanilloids, including capsaicin and eugenol, are ligands of transient receptor potential channel vanilloid subfamily member 1 (TRPV1). Prolonged treatment with vanilloids triggered the desensitization of TRPV1, leading to analgesic or antinociceptive ... -
Single-step production of autologous bovine platelet concentrate for clinical applications in cattle
(Elsevier, 2022-11-21)Platelet concentrate (PC) is an alternative therapy to treat mastitis in dairy cattle and is an alternative treatment for reproduction problems such as endometritis. Unfortunately, double-centrifugation processing methods described are time-consuming, ... -
Is nontargeted data acquisition for target analysis (nDATA) in mass spectrometry a forward-thinking analytical approach?
(Wiley, 2022-10-21)Targeted mass spectrometry is extensively used for the quantitative measurement of various molecules present in complex matrices. It is certainly one of the most important analytical duties in a mass spectrometry laboratory. Systematic development of ... -
Comparative full genome sequence analysis of wild-type and chicken embryo origin vaccine-like infectious laryngotracheitis virus field isolates from Canada
(Elsevier, 2022-08-14)Infectious laryngotracheitis (ILT), caused by infectious laryngotracheitis virus (ILTV), occurs sporadically in poultry flocks in Canada. Live attenuated chicken embryo origin (CEO) vaccines are being used routinely to prevent and control ILTV infections. ... -
Leishmania parasites exchange drug-resistance genes through extracellular vesicles
(2022-07-19)Leishmania are eukaryotic parasites that have retained the ability to produce extracellular vesicles (EVs) through evolution. To date, it has been unclear if different DNA entities could be associated with Leishmania EVs and whether these could constitute ... -
Proteomics reveals long-term alterations in signaling and metabolic pathways following both myocardial infarction and chemically induced denervation
(Elsevier, 2022-06-18)Myocardial infraction (MI) is the principal risk factor for the onset of heart failure (HF). Investigations regarding the physiopathology of MI progression to HF have revealed the concerted engagement of other tissues, such as the autonomic nervous ... -
Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs
(Wiley, 2022-05-30)Introduction: Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs. Methods: To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan ... -
Evaluation of the safety of multiple intramuscular doses of ketoprofen in bearded dragons (Pogona vitticeps)
(Association of reptilian and amphibian veterinarians, 2022-05-30)Cyclooxygenase (COX) 1 has been shown to increase significantly in inflamed ophidian skin and chelonian muscles. Nonselective COX-1 and COX-2 inhibitors, such as ketoprofen, could therefore reduce inflammation more effectively than preferential COX-2 ... -
Evaluation of the safety of multiple intramuscular doses of ketoprofen in bearded dragons (Pogona vitticeps)
(Association of reptilian and amphibian veterinarians, 2022-05-30)Cyclooxygenase (COX) 1 has been shown to increase significantly in inflamed ophidian skin and chelonian muscles. Nonselective COX-1 and COX-2 inhibitors, such as ketoprofen, could therefore reduce inflammation more effectively than preferential COX-2 ... -
Coding-complete genome sequence of a Falcon aviadenovirus A strain associated with necrotizing hepatitis in an American Kestrel (Falco sparverius)
(American Society for Microbiology, 2022-03-17)A necropsy was performed on an American kestrel (Falco sparverius) with necrotizing hepatitis associated with inclusion bodies, suggesting an adenovirus infection. A next-generation sequencing assay was conducted on the liver, and the coding-complete ... -
Untargeted and targeted metabolomics reveal that adenosine nucleotides released in Actinobacillus pleuropneumoniae supernatant inhibit porcine reproductive and respiratory syndrome virus replication
(Elsevier, 2022-02-18)Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most devastating viruses in the swine industry and causes major economic losses. To date, there has not been an effective antiviral treatment for the disease. We have shown in ... -
Quebec : avian pathogens identification and genomic characterization : 2021 annual review of the Molecular Diagnostic Laboratory, Université de Montréal
(Canadian veterinary medical association, 2022)