Recherche
Voici les éléments 1-10 de 17
A prognostic tool to identify youth at risk of at least weekly cannabis use
(Springer, 2022-03-09)
We developed and validated an 8-item prognostic tool to identify youth
at risk of initiating frequent (i.e., at least weekly) cannabis use in the next year. The
tool, which aims to identify youth who would benefit most ...
Revisiting trajectories of BMI in youth : an in‐depth analysis of differences between BMI and other adiposity measures
(Wiley, 2021-06-16)
Objective
Body mass index (BMI) is used to identify trajectories of adiposity in youth, but it does not distinguish fat- from fat-free-mass. There are other inexpensive measures of adiposity which might better capture ...
Discrete time measures versus trajectories of drinking frequency across adolescence as predictors of binge drinking in young adulthood : a longitudinal investigation
(BMJ Publishing Group, 2020-09-23)
Objectives We compared discrete time measures with
trajectories of adolescent drinking frequency as predictors
of sustained binge drinking in young adulthood.
Design Prospective longitudinal study.
Setting 10 high ...
Missing single nucleotide polymorphisms in Genetic Risk Scores : a simulation study
(Public Library of Science, 2018-07-19)
Using a genetic risk score (GRS) to predict a phenotype in a target sample can be complicated by missing data on the single nucleotide polymorphisms (SNPs) that comprise the GRS. This is usually addressed by imputation, ...
Self-reported weight loss attempts and weight-related stress in childhood : heightening the risk of obesity in early adolescence
(Wiley, 2021-01-26)
Objective
Weight loss attempts occur as early as childhood. The impacts of weight loss attempts and weight-related stress on the occurrence of obesity during childhood remain unknown. We aimed to: (a) assess the prevalence ...
Association of genetic variants with body-mass index and blood pressure in adolescents : a replication study
(Frontiers Media, 2021-09-01)
The strong correlation between adiposity and blood pressure (BP) might be explained in
part by shared genetic risk factors. A recent study identified three nucleotide variants
[rs16933812 (PAX5), rs7638110 (MRPS22), and ...
Strategies to increase the demand for childhood vaccination in lowand middle-income countries : a systematic review and meta-analysis
(World Health Organization, 2015)
Objective To investigate which strategies to increase demand for vaccination are effective in increasing child vaccine coverage in low- and
middle-income countries.
Methods We searched MEDLINE, EMBASE, Cochrane library, ...
Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents
(Public Library of Science, 2014-12-29)
Background: While the heritability of cigarette smoking and nicotine dependence
(ND) is well-documented, the contribution of specific genetic variants to specific
phenotypes has not been closely examined. The objectives ...
Mendelian randomization : a review of methods for the prevention, assessment, and discussion of pleiotropy in studies using the fat mass and obesity-associated gene as an instrument for adiposity
(Frontiers Media, 2022-02-04)
Pleiotropy assessment is critical for the validity of Mendelian randomization (MR) analyses, and its management remains a challenging task for researchers. This review examines how the authors of MR studies address bias ...
A longitudinal study of change in substance use from before to during the COVID-19 pandemic in young adults
(Elsevier, 2022-01-06)
Introduction We assessed change in substance use from before to during the COVID-19 pandemic in young adults
and identified factors associated with initiation/increase in use.
Methods The sample comprised young adults ...