Browsing École de santé publique – Travaux et publications by Author "O’Loughlin, Jennifer"
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Association of genetic variants with body-mass index and blood pressure in adolescents : a replication study
Goulet, Danick; O’Loughlin, Jennifer; Sylvestre, Marie-Pierre (Frontiers Media, 2021-09-01)The strong correlation between adiposity and blood pressure (BP) might be explained in part by shared genetic risk factors. A recent study identified three nucleotide variants [rs16933812 (PAX5), rs7638110 (MRPS22), and rs9930333 (FTO)] associated ... -
Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents
O’Loughlin, Jennifer; Sylvestre, Marie-Pierre; Labbe, Aurélie; Low, Nancy C.; Roy-Gagnon, Marie-Hélène; Dugas, Erika N.; Karp, Igor; Engert, James C. (Public Library of Science, 2014-12-29)Background: While the heritability of cigarette smoking and nicotine dependence (ND) is well-documented, the contribution of specific genetic variants to specific phenotypes has not been closely examined. The objectives of this study were to test ... -
Missing single nucleotide polymorphisms in Genetic Risk Scores : a simulation study
Chagnon, Miguel; O’Loughlin, Jennifer; Engert, James C.; Karp, Igor; Sylvestre, Marie-Pierre (Public Library of Science, 2018-07-19)Using a genetic risk score (GRS) to predict a phenotype in a target sample can be complicated by missing data on the single nucleotide polymorphisms (SNPs) that comprise the GRS. This is usually addressed by imputation, omission of the SNPs or by ... -
Stable physical activity patterns predominate in a longitudinal study of physical activity among young adults in Canada from before to during the COVID-19 pandemic
O’Loughlin, Erin K.; Riglea, Teodora; Sylvestre, Marie-Pierre; Pelekanakis, Annie; Sabiston, Catherine M.; Bélanger, Mathieu; O’Loughlin, Jennifer (Elsevier, 2022-03-29)We examined change in walking, moderate-to-vigorous physical activity (MVPA) and meeting MVPA guidelines from before to during the COVID-19 pandemic, and identified factors associated with newly meeting and no longer meeting MVPA guidelines during ... -
Symptoms of depression and anxiety increased marginally from before to during the COVID-19 pandemic among young adults in Canada
Sylvestre, Marie-Pierre; Tchouangue Dinkou, Gillis Delmas; Armasu, Alexia; Pelekanakis, Annie; Plourde, Vickie; Bélanger, Mathieu; Maximova, Katerina; Thombs, Brett D.; O’Loughlin, Jennifer (Nature research, 2022-09-26)We documented changes in depressive and anxiety symptoms from before to during the COVID-19 pandemic among young adults and investigated whether changes differed across participant characteristics. Data were available in an investigation of 1294 grade ...