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Parcourir École de santé publique – Travaux et publications par sujet "Mendelian randomization"
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Mendelian randomization : a review of methods for the prevention, assessment, and discussion of pleiotropy in studies using the fat mass and obesity-associated gene as an instrument for adiposity
(Frontiers Media, 2022-02-04)Pleiotropy assessment is critical for the validity of Mendelian randomization (MR) analyses, and its management remains a challenging task for researchers. This review examines how the authors of MR studies address bias due to pleiotropy in practice. ...