Parcourir École de santé publique – Travaux et publications par auteur·e "Sylvestre, Marie-Pierre"
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Association of genetic variants with body-mass index and blood pressure in adolescents : a replication study
Goulet, Danick; O’Loughlin, Jennifer; Sylvestre, Marie-Pierre (Frontiers Media, 2021-09-01)The strong correlation between adiposity and blood pressure (BP) might be explained in part by shared genetic risk factors. A recent study identified three nucleotide variants [rs16933812 (PAX5), rs7638110 (MRPS22), and rs9930333 (FTO)] associated ... -
The change in exergaming from before to during the COVID-19 pandemic among young adults : longitudinal study
O’Loughlin, Erin K.; Sabiston, Catherine M.; O'Rourke, Roxy H.; Bélanger, Mathieu; Sylvestre, Marie-Pierre; O'Loughlin, Jennifer (JMIR Publications, 2023-05-22)Background: Exergaming may be an important option to support an active lifestyle, especially during pandemics. Objective: Our objectives were (1) to explore whether change in exergaming status (stopped, started or sustained exergaming, or never ... -
Discrete time measures versus trajectories of drinking frequency across adolescence as predictors of binge drinking in young adulthood : a longitudinal investigation
Sylvestre, Marie-Pierre; Wellman, Robert J.; Ahun, Marilyn N.; Datta, Geetanjali; Jutras-Aswad, Didier; O'Loughlin, Jennifer (BMJ Publishing Group, 2020-09-23)Objectives We compared discrete time measures with trajectories of adolescent drinking frequency as predictors of sustained binge drinking in young adulthood. Design Prospective longitudinal study. Setting 10 high schools in Montréal, Canada. Participants ... -
Do social characteristics influence smoking uptake and cessation during young adulthood?
Steinmetz-Wood, Madeleine; Gagné, Thierry; Sylvestre, Marie-Pierre; Frohlich, Katherine L. (2017-10-29)Objectives This study uses a Bourdieusian approach to assess young adults’ resources and examines their association with smoking initiation and cessation. Methods Data were drawn from 1450 young adults participating in the Interdisciplinary ... -
Estimating causal effects of physical activity and sedentary behaviours on the development of type 2 diabetes in at-risk children from childhood to late adolescence : an analysis of the QUALITY cohort
Harnois-Leblanc, Soren; Sylvestre, Marie-Pierre; Van Hulst, Andraea; Barnett, Tracie A.; Mathieu, Marie-Ève; Mésidor, Miceline; McGrath, Jennifer J.; Tremblay, Angelo; Drapeau, Vicky; Paradis, Gilles; Henderson, Mélanie (Elsevier, 2022-11-07)Background. Uncertainty remains regarding the causal effect of physical activity and sedentary behaviors on type 2 diabetes (T2D) development in children. The objective of our study was to estimate average treatment effects (ATEs) of physical activity ... -
Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents
O’Loughlin, Jennifer; Sylvestre, Marie-Pierre; Labbe, Aurélie; Low, Nancy C.; Roy-Gagnon, Marie-Hélène; Dugas, Erika N.; Karp, Igor; Engert, James C. (Public Library of Science, 2014-12-29)Background: While the heritability of cigarette smoking and nicotine dependence (ND) is well-documented, the contribution of specific genetic variants to specific phenotypes has not been closely examined. The objectives of this study were to test ... -
A longitudinal study of change in substance use from before to during the COVID-19 pandemic in young adults
Sylvestre, Marie-Pierre; Tchouangue Dinkou, Gillis Delmas; Naja, Mounia; Riglea, Teodora; Pelekanakis, Annie; Bélanger, Mathieu; Maximova, Katerina; Mowat, David; Paradis, Gilles (Elsevier, 2022-01-06)Introduction We assessed change in substance use from before to during the COVID-19 pandemic in young adults and identified factors associated with initiation/increase in use. Methods The sample comprised young adults from a longitudinal investigation ... -
Mendelian randomization : a review of methods for the prevention, assessment, and discussion of pleiotropy in studies using the fat mass and obesity-associated gene as an instrument for adiposity
Mbutiwi, Fiston Ikwa Ndol; Dessy, Tatiana; Sylvestre, Marie-Pierre (Frontiers Media, 2022-02-04)Pleiotropy assessment is critical for the validity of Mendelian randomization (MR) analyses, and its management remains a challenging task for researchers. This review examines how the authors of MR studies address bias due to pleiotropy in practice. ... -
Missing single nucleotide polymorphisms in Genetic Risk Scores : a simulation study
Chagnon, Miguel; O’Loughlin, Jennifer; Engert, James C.; Karp, Igor; Sylvestre, Marie-Pierre (Public Library of Science, 2018-07-19)Using a genetic risk score (GRS) to predict a phenotype in a target sample can be complicated by missing data on the single nucleotide polymorphisms (SNPs) that comprise the GRS. This is usually addressed by imputation, omission of the SNPs or by ... -
Natural history and determinants of dysglycemia in Canadian children with parental obesity from ages 8–10 to 15–17 years : the QUALITY cohort
Harnois-Leblanc, Soren; Van Hulst, Andraea; Ybarra, Marina; Barnett, Tracie A.; Mathieu, Marie-Ève; McGrath, Jennifer J.; Tremblay, Angelo; Paradis, Gilles; Drapeau, Vicky; Sylvestre, Marie-Pierre; Henderson, Mélanie (Wiley, 2022-01-13)In children, the mechanisms implicated in deterioration of glucose homeostasis versus reversion to normal glucose tolerance (NGT) remain uncertain. We aimed to describe the natural history of dysglycemia from childhood to late adolescence and to identify ... -
A prognostic tool to identify youth at risk of at least weekly cannabis use
Sylvestre, Marie-Pierre; De Montigny, Simon; Boulanger, Laurence; Goulet, Danick; Doré, Isabelle; O'Loughlin, Jennifer; Haddad, Slim; Bélanger, Richard E.; Leatherdale, Scott (Springer, 2022-03-09)We developed and validated an 8-item prognostic tool to identify youth at risk of initiating frequent (i.e., at least weekly) cannabis use in the next year. The tool, which aims to identify youth who would benefit most from clinician intervention, ... -
Revisiting trajectories of BMI in youth : an in‐depth analysis of differences between BMI and other adiposity measures
Sylvestre, Marie-Pierre; Ahun, Marilyn N.; O'Loughlin, Jennifer (Wiley, 2021-06-16)Objective Body mass index (BMI) is used to identify trajectories of adiposity in youth, but it does not distinguish fat- from fat-free-mass. There are other inexpensive measures of adiposity which might better capture fat-mass in youth The objective ... -
Self-reported weight loss attempts and weight-related stress in childhood : heightening the risk of obesity in early adolescence
Harnois-Leblanc, Soren; Van Hulst, Andraea; Sabiston, Catherine M.; Maximova, Katerina; Béland, Mélanie; Doré, Isabelle; Sylvestre, Marie-Pierre; Henderson, Mélanie (Wiley, 2021-01-26)Objective Weight loss attempts occur as early as childhood. The impacts of weight loss attempts and weight-related stress on the occurrence of obesity during childhood remain unknown. We aimed to: (a) assess the prevalence of self-reported weight loss ... -
Stable physical activity patterns predominate in a longitudinal study of physical activity among young adults in Canada from before to during the COVID-19 pandemic
O’Loughlin, Erin K.; Riglea, Teodora; Sylvestre, Marie-Pierre; Pelekanakis, Annie; Sabiston, Catherine M.; Bélanger, Mathieu; O’Loughlin, Jennifer (Elsevier, 2022-03-29)We examined change in walking, moderate-to-vigorous physical activity (MVPA) and meeting MVPA guidelines from before to during the COVID-19 pandemic, and identified factors associated with newly meeting and no longer meeting MVPA guidelines during ... -
Strategies to increase the demand for childhood vaccination in lowand middle-income countries : a systematic review and meta-analysis
Johri, Mira; Pérez Osorio, Myriam Cielo; Arsenault, Catherine; Sharma, Jitendar K.; Pai, Nitika Pant; Pahwa, Smriti; Sylvestre, Marie-Pierre (World Health Organization, 2015)Objective To investigate which strategies to increase demand for vaccination are effective in increasing child vaccine coverage in low- and middle-income countries. Methods We searched MEDLINE, EMBASE, Cochrane library, POPLINE, ECONLIT, CINAHL, ... -
Supplementary material for : Natural history and determinants of dysglycemia in Canadian children with parental obesity from ages 8-10 to 15-17 years : the QUALITY Cohort
Harnois-Leblanc, Soren; Van Hulst, Andraea; Ybarra, Marina; Barnett, Tracie A.; Mathieu, Marie-Ève; McGrath, Jennifer J.; Tremblay, Angelo; Paradis, Gilles; Drapeau, Vicky; Sylvestre, Marie-Pierre; Henderson, Mélanie (2021-08-03) -
Symptoms of depression and anxiety increased marginally from before to during the COVID-19 pandemic among young adults in Canada
Sylvestre, Marie-Pierre; Tchouangue Dinkou, Gillis Delmas; Armasu, Alexia; Pelekanakis, Annie; Plourde, Vickie; Bélanger, Mathieu; Maximova, Katerina; Thombs, Brett D.; O’Loughlin, Jennifer (Nature research, 2022-09-26)We documented changes in depressive and anxiety symptoms from before to during the COVID-19 pandemic among young adults and investigated whether changes differed across participant characteristics. Data were available in an investigation of 1294 grade ...