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Evidence of white matter changes on diffusion tensor imaging in frontotemporal dementia
(American Medical Association, 2007)
BACKGROUND:
Two major clinical variants of frontotemporal dementia (FTD) have been described: frontal variant (fvFTD) and temporal variant (tvFTD).
OBJECTIVE:
To analyze white matter (WM) and gray matter (GM) tissue ...
White matter changes in corticobasal degeneration syndrome and correlation with limb apraxia
(American Medical Association, 2008)
BACKGROUND:
Data on white matter changes in corticobasal degeneration syndrome (CBDS) are not yet available, whereas cortical gray matter loss is a feature of this condition. The structural abnormalities related to a key ...
The anatomy of category-specific object naming in neurodegenerative diseases
(Massachusetts Institute of Technology Press, 2006)
Neuropsychological studies suggest that knowledge about
living and nonliving objects is processed in separate brain regions. However, lesion and functional neuroimaging studies
have implicated different areas. To address ...
Single and Multiple Domain Amnestic MCI: two sides of the same coin?
Single- and multiple-domain amnestic mild cognitive impairment: two sides of the same coin?
(2009)
Background. Amnestic Mild Cognitive Impairment (aMCI) is considered a transition
stage between normal aging and Alzheimer's disease (AD). Two main clinical subtypes
of aMCI have been identified: 1) aMCI single domain ...
Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease
(Cambridge University Press, 2009)
Good cognitive performance requires adherence to rules specific to the task at hand. Patients with neurological disease often make rule violation errors, but the anatomical basis for rule violation during cognitive testing ...
The neural correlates of verbal and nonverbal semantic processing deficits in neurodegenerative disease
(Lippincott, Williams & Wilkins, 2009)
Objective—To investigate the neural correlates of verbal and non-verbal semantic processing in
neurodegenerative disease.
Background—Semantic memory is often impaired in neurodegenerative disease.
Neuropsychological and ...
Regional reductions of gray matter volume in familial dyslexia
(American Academy of Neurology, 2004)
An in vivo anatomic study of gray matter volume was performed in a group of familial dyslexic individuals,
using an optimized method of voxel-based morphometry. Focal abnormalities in gray matter volume were observed
bilaterally ...
The logopenic/phonological variant of primary progressive aphasia
(American Academy of Neurology, 2008)
Objective: Primary progressive aphasia (PPA) is characterized by isolated decline in language
functions. Semantic dementia and progressive nonfluent aphasia are accepted PPA variants. A
“logopenic” variant (LPA) has also ...
Regional brain stem atrophy in idiopathic Parkinson's disease detected by anatomical MRI
(Public Library of Science, 2009-12-10)
Idiopathic Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the dysfunction of dopaminergic
dependent cortico-basal ganglia loops and diagnosed on the basis of motor symptoms (tremors and/or ...
Anatomical correlates of early mutism in progressive nonfluent aphasia
(American Academy of Neurology, 2006)
Patients with progressive nonfluent aphasia (PNFA) can become
mute early in the course of the disease. Voxel-based morphometry showed that
PNFA is associated with left anterior insula and inferior frontal atrophy. In
...