• Anatomical correlates of early mutism in progressive nonfluent aphasia 

    Gorno-Tempini, Maria Luisa; Ogar, Jennifer M.; Brambati, Simona Maria; Wang, P.; Jeong, Je Hoon; Rankin, Katherine P.; Dronkers, Nina; Miller, Bruce L. (American Academy of Neurology, 2006)
    Patients with progressive nonfluent aphasia (PNFA) can become mute early in the course of the disease. Voxel-based morphometry showed that PNFA is associated with left anterior insula and inferior frontal atrophy. In PNFA with early mutism, volume ...
  • The anatomy of category-specific object naming in neurodegenerative diseases 

    Brambati, Simona Maria; Myers, D.; Wilson, A.; Rankin, Katherine P.; Allison, Stephen C.; Rosen, Howard J.; Miller, Bruce L.; Gorno-Tempini, Maria Luisa (Massachusetts Institute of Technology Press, 2006)
    Neuropsychological studies suggest that knowledge about living and nonliving objects is processed in separate brain regions. However, lesion and functional neuroimaging studies have implicated different areas. To address this issue, we used voxel-based ...
  • Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer’s disease 

    Chapleau, Marianne; Bedetti, Christophe; Devenyi, Gabriel A.; Sheldon, Signy; Rosen, Howard J.; Miller, Bruce L.; Gorno-Tempini, Maria Luisa; Chakravarty, Mallar M.; Brambati, Simona Maria (Elsevier, 2020-06-03)
    Background Increasing evidence shows that the semantic variant of primary progressive aphasia (svPPA) is characterized by hippocampal atrophy. However, less is known about disease-related morphological hippocampal changes. The goal of the present study ...
  • The logopenic/phonological variant of primary progressive aphasia 

    Gorno-Tempini, Maria Luisa; Brambati, Simona Maria; Ginex, Valeria; Ogar, Jennifer M.; Dronkers, Nina; Marcone, Alessandra; Perani, Daniela; Garibotto, Valentina; Cappa, Stefano F.; Miller, Bruce L. (American Academy of Neurology, 2008)
    Objective: Primary progressive aphasia (PPA) is characterized by isolated decline in language functions. Semantic dementia and progressive nonfluent aphasia are accepted PPA variants. A “logopenic” variant (LPA) has also been proposed, but its cognitive ...
  • Longitudinal gray matter contraction in three variants of primary progressive aphasia : a tensor-based morphometry study 

    Brambati, Simona Maria; Amici, Serena; Racine, Caroline A.; Neuhaus, John; Miller, Zachary; Ogar, Jennifer M.; Dronkers, Nina; Miller, Bruce L.; Rosen, Howard J.; Gorno-Tempini, Maria Luisa (Elsevier, 2015-01-22)
    The present study investigated the pattern of longitudinal changes in cognition and anatomy in three variants of primary progressive aphasia (PPA). Eight patients with the non-fluent variant of PPA (nfvPPA), 13 patients with the semantic variant (svPPA), ...
  • Music recognition in frontotemporal lobar degeneration and Alzheimer disease 

    Johnson, Julene K.; Chang, Chiung-Chih; Brambati, Simona Maria; Migliaccio, Raffaella; Gorno-Tempini, Maria Luisa; Miller, Bruce L.; Janata, Petr (Lippincott, Williams & Wilkins, 2011-06)
    Objective—To compare music recognition in patients with frontotemporal dementia, semantic dementia, Alzheimer disease, and controls and to evaluate the relationship between music recognition and brain volume. Background—Recognition of familiar music ...
  • The neural correlates of verbal and nonverbal semantic processing deficits in neurodegenerative disease 

    Butler, Christopher R.; Brambati, Simona Maria; Miller, Bruce L.; Gorno-Tempini, Maria Luisa (Lippincott, Williams & Wilkins, 2009)
    Objective—To investigate the neural correlates of verbal and non-verbal semantic processing in neurodegenerative disease. Background—Semantic memory is often impaired in neurodegenerative disease. Neuropsychological and functional neuroimaging studies ...
  • Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease 

    Possin, Katherine L.; Brambati, Simona Maria; Rosen, Howard J.; Johnson, Julene K.; Pa, Judy; Weiner, Michael W.; Miller, Bruce L.; Kramer, Joel H. (Cambridge University Press, 2009)
    Good cognitive performance requires adherence to rules specific to the task at hand. Patients with neurological disease often make rule violation errors, but the anatomical basis for rule violation during cognitive testing remains debated. The current ...