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Understanding and diagnosing the potential for bias when using machine learning methods with doubly robust causal estimators
(SAGE, 2018-05-02)
Data-adaptive methods have been proposed to estimate nuisance parameters when using doubly robust semiparametric methods for estimating marginal causal effects. However, in the presence of near practical positivity violations, ...
Resistance and mutations of non-specificity in the field of anxietydepressive disorders in Canadian medical journals, 1950-1990
(Elsevier, 2014-12-03)
Pharmaceuticalisation is a complex phenomenon, co-constitutive of what scholars identify as a pharmaceutical
regime, comprised of networks of actors, institutions and artefacts as well as cognitive
structures that underlie ...
Head‐to‐Head comparison of consensus‐recommended platelet function tests to assess P2Y12 Inhibition : insights for multi‐center trials
(MDPI, 2020)
The vasodilator‐associated stimulated phosphoprotein (VASP) phosphorylation level is a
highly specific method to assess P2Y12 receptor inhibition. Traditionally, VASP phosphorylation is
analyzed by flow cytometry, which ...
Study of the bioaccumulation of tinzaparin in renally impaired patients when given at prophylactic doses : The STRIP study
Prophylactic tinzaparin in severe renal disease
(Elsevier, 2018-12-02)
Nanonization of megestrol acetate by laser fragmentation in aqueous milieu
(2011-02-10)
Nanonization is a simple and effective method to improve dissolution rate and oral
bioavailability of drugs with poor water solubility. There is growing interest to downscale the nanocrystal production to enable early ...
Causal inference with multiple concurrent medications: a comparison of methods and an application in multidrug-resistant tuberculosis
(SAGE, 2018-10-31)
This paper investigates different approaches for causal estimation under multiple concurrent medications. Our parameter of interest is the marginal mean counterfactual outcome under different combinations of medications. ...
Platelet function tests
(Thieme Publishing, 2016-04)
Traditionally developed for diagnosis of bleeding disorders, platelet function assays have
become increasingly used in basic research on platelet physiology, in phenotype-genotype
associations in bleeding disorders, in ...
Rationing hepatitis C treatment in the context of austerity policies in France and Cameroon : a transnational perspective on thepharmaceuticalization of healthcare systems
(Elsevier, 2017-03-28)
New powerful drugs against hepatitis C can cure the disease, but they are not widely distributed because their exorbitant prices are destabilizing healthcare systems in both African and European countries. This article ...
Étude des interactions entre les nanoparticules et les matrices biologiques par microscopie différentielle dynamique
(2022-05-11)
Nanomedicine is based primarily on the concept of drug formulation through nanotechnology. The main idea is based on the encapsulation of an active ingredient by a nanoparticle (NP) to allow it to accumulate in tumors, to ...