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Eugenol and other vanilloids hamper caenorhabditis elegans response to noxious heat
(Springer, 2020-10-29)
Eugenol, a known vanilloid, was frequently used in dentistry as a local analgesic in addition, antibacterial and neuroprotective effects were also reported. Eugenol, capsaicin and many vanilloids are interacting with the ...
Antinociceptive activity of vanilloids in caenorhabditis elegans is mediated by the desensitization of the TRPV channel OCR-2 and specific signal transduction pathways
(Springer, 2023-02-03)
Vanilloids, including capsaicin and eugenol, are ligands of transient receptor potential channel vanilloid subfamily member 1 (TRPV1). Prolonged treatment with vanilloids triggered the desensitization of TRPV1, leading to ...
Capsaicin and Its analogues impede nocifensive response of caenorhabditis elegans to noxious heat
(2020-05-05)
Capsaicin is the most abundant pungent molecule identifed in red chili peppers, and it is widely used for food favoring,
in pepper spray for self-defense devices and recently in ointments for the relief of neuropathic ...