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Liquid Chromatography-Electrospray Linear Ion Trap Mass Spectrometry Analysis of Targeted Neuropeptides in Tac1-/- Mouse Spinal Cords Reveal Significant Lower Concentration of Opioid Peptides
(2015-08)
Tachykinin and opioid peptides play a central role in pain transmission, modulation and
inhibition. The treatment of pain is very important in medicine and many studies using NK1
receptor antagonists failed to show ...
Evaluation of multiple reaction monitoring cubed for the analysis of tachykinin related peptides in rat spinal cord using a hybrid triple quadrupole–linear ion trap mass spectrometer
(2014-02)
Targeted peptide methods generally use HPLC-MS/MRM approaches. Although dependent on
the instrumental resolution, interferences may occur while performing analysis of complex
biological matrices. HPLC-MS/MRM3 is a ...