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Characterization of Endoproteolytic Processing of Dynorphins by Proprotein Convertases using Mouse Spinal Cord S9 Fractions and Mass Spectrometry
(2016-06-01)
Dynorphins are important neuropeptides with a central role in nociception and pain alleviation. Many mechanisms regulate endogenous dynorphin concentrations, including proteolysis. Proprotein convertases (PCs) are widely ...
Tachykinins Processing is Significantly Impaired in PC1 and PC2 Mutant Mouse Spinal Cord S9 Fractions
(2015-11-01)
Substance P (SP) play a central role in nociceptive transmission and it is an agonist of the
Neurokinin-1 receptor located in the lamina I of the spinal cord. SP is a major proteolytic product
of the protachykinin-1 ...
Case Report: Esophagitis and pharyngitis associated with avian infectious laryngotracheitis in backyard chickens: 2 cases
(2017-06)
Infectious laryngotracheitis (ILT) is a contagious viral respiratory disease of great economic importance for the global poultry industry caused by Gallid herpesvirus 1 (GaHV-1). Lesions of the upper digestive tract caused ...
Comparative full genome sequence analysis of wild-type and chicken embryo origin vaccine-like infectious laryngotracheitis virus field isolates from Canada
(Elsevier, 2022-08-14)
Infectious laryngotracheitis (ILT), caused by infectious laryngotracheitis virus (ILTV), occurs sporadically in poultry flocks in Canada. Live attenuated chicken embryo origin (CEO) vaccines are being used routinely to ...
Gastric stability and oral bioavailability of colistin sulfate in pigs challenged or not with Escherichia coli O149: F4 (K88)
(2015-10)
The aim of the present study was to investigate the in vitro gastric stability of colistin sulfate (CS) and its antimicrobial activity against Escherichia coli and to study the impact of ETEC O149: F4 (K88) infection in ...
Single-step production of autologous bovine platelet concentrate for clinical applications in cattle
(Elsevier, 2022-11-21)
Platelet concentrate (PC) is an alternative therapy to treat mastitis in dairy cattle and is an alternative treatment for reproduction problems such as endometritis. Unfortunately, double-centrifugation processing methods ...
Porcine circovirus modulates swine influenza virus replication in pig tracheal epithelial cells and porcine alveolar macrophages
(MDPI, 2023-05-20)
The pathogenesis of porcine circovirus type 2b (PCV2b) and swine influenza A virus
(SwIV) during co-infection in swine respiratory cells is poorly understood. To elucidate the impact
of PCV2b/SwIV co-infection, newborn ...
Assessment of meat authenticity using bioinformatics, targeted peptide biomarkers and high-resolution mass spectrometry
(2015-10-01)
In recent years, we observed a significant increase of food fraud ranging from false label claims to the use of additives and fillers to increase profitability. Recently in 2013, horse and pig DNA were detected in beef ...
Dual infections of CD163 expressing NPTr epithelial cells with influenza A virus and PRRSV
(2017-08)
In the pig, respiratory co-infections involving various pathogens are far more frequent than single infections.
Amongst respiratory viruses, swine influenza type A virus (swIAV) and porcine reproductive and respiratory
syndrome ...
The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis
(2010)
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral
disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV),
possesses a RNA viral genome with nine ...