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Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly
(Elsevier, 2015-01-01)
In a recent study, the serotype 3 Dearing strain of mammalian orthoreovirus was adapted to Vero cells; cells that exhibit a limited ability to support the early steps of reovirus uncoating and are unable to produce interferon ...
Ethical Issues Raised by Private Practice Physiotherapy Are More Diverse than First Meets the Eye: Recommendations from a Literature Review
(2015)
Purpose: Physiotherapy in private practice differs from physiotherapy practised in a public setting in several ways, the most evident of which is the for-profit nature of private physiotherapy clinics; these differences ...
The Contribution of Conceptual Frameworks to Knowledge Translation Interventions in Physical Therapy
(2015-04-01)
Context:
There is growing recognition of the importance of knowledge translation activities in physical therapy to ensure that research findings are integrated in clinical practice, and increasing numbers of knowledge ...
Trajectories of gambling problems from mid-adolescence to age 30 in a general population cohort
(American Psychological Association, 2015-12)
Studies of gambling starting before adulthood in the general population are either cross-sectional, based on the stability of these behaviors between 2 time points, or cover a short developmental period. The present study ...
Variety of gambling activities from adolescence to age 30 and association with gambling problems: a 15‐year longitudinal study of a general population sample
Variety of gambling activities
(Wiley, 2015-12)
Participants
A mixed‐gender general population cohort assessed at ages 15 (n = 1882), 22 (n = 1785) and 30 (n = 1358).
Measurements
Adolescent and adult versions of the South Oaks Gambling Screen (SOGS).
Findings
Group‐based ...
How fast and how often: the pharmacokinetics of drug use are decisive in addiction
(2015-09)
How much, how often and how fast a drug reaches the brain determine the behavioural and neuroplastic changes associated with the
addiction process. Despite the critical nature of these variables, the drug addiction field ...
Associations of substance use patterns with attempted suicide among persons who inject drugs: Can distinct use patterns play a role?
(Elsevier, 2015-02-01)
Background: While the elevated risk of suicide attempt among persons who inject drugs
(PWID) is well documented, whether use of different substances is associated with varying
degrees of risk remains unclear. We sought ...
The effect of social functioning and living arrangement on treatment intent, specialist assessment and treatment uptake for hepatitis C virus infection among people who inject drugs: the ETHOS study
(Elsevier, 2015-11)
Background: The objective was to assess social functioning and its association with treatment intent, specialist assessment and treatment uptake for hepatitis C virus (HCV) infection among people with a history of injecting ...
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection
(American Association for the Advancement of Science, 2015-12-16)
Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ
transplant recipients. However, mechanisms of immunization to apoptotic components remain largely ...
Correlated gene expression supports synchronous activity in brain networks
(American Association for the Advancement of Science, 2015-06-12)
During rest, brain activity is synchronized between different regions widely distributed throughout the brain, forming functional networks. However, the molecular mechanisms supporting functional connectivity remain ...