Search
Now showing items 21-30 of 82
Ten simple rules for conducting a mendelian randomization study
(Public Library of Science, 2021)
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: In vivo mouse model
(2009)
The secretory basic amino acid-specific proprotein convertases (PCs) have often been associated with cancer/metastasis. By controlling the cleavage of cancer-associated proteins, PCs play key roles in multiple steps of ...
Development and disease of the photoreceptor cilium
(2009)
Primary cilia are microtubule-rich hair-like extensions protruding from the surface of most post-mitotic cells. They act as sensory organelles that help interpret various environmental cues. Mutations in genes encoding ...
Nutritional strategies to manage malnutrition and sarcopenia following liver transplantation : a narrative review
(MDPI, 2023-02-10)
Persisting or newly developed malnutrition and sarcopenia after liver transplant (LT) are correlated with adverse health outcomes. This narrative review aims to examine the literature regarding nutrition strategies to ...
Astrocyte glutamine synthetase : pivotal in health and disease
(Portland Press, 2013)
The multifunctional properties of astrocytes signify their importance in brain physiology and neurological function. In addition to defining the brain architecture, astrocytes are primary elements of brain ion, pH and ...
Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats
(Wiley, 2013-11-25)
Background & Aims The pathogenesis of hepatic encephalopathy (HE) is multifactorial and often associated with the
development of brain oedema. In addition to ammonia playing a central role, systemic oxidative stress is ...
Elevated cerebral lactate : implications in the pathogenesis of hepatic encephalopathy
(Springer, 2014-06-11)
Hepatic encephalopathy (HE), a complex neuropsychiatric syndrome, is a frequent complication of liver
failure/disease. Increased concentrations of lactate are commonly observed in HE patients, in the systemic circulation,
but ...
Judging the value of ammonia measurement on lactulose dosing : apples and oranges?
(University of Toronto Press, 2021-02-24)
The euchromatic and heterochromatic landscapes are shaped by antagonizing effects of transcription on H2A.Z deposition
(2009)
A role for variant histone H2A.Z in gene expression is now well established but little is known about the mechanisms by which it operates. Using a combination of ChIP-chip, knockdown and expression profiling experiments, ...