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Neuropathological changes in the brain of pigs with acute liver failure
(2010-08)
Abstract Objective. Cerebral edema is a serious complication of acute liver failure (ALF), which may lead to intracranial hypertension and death. An accepted tenet has been that the blood-brain barrier is intact and that ...
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure
(2012-04)
Chronic liver failure leads to hyperammonemia, a central component in the pathogenesis of hepatic encephalopathy (HE); however, a correlation between blood ammonia levels and HE severity remains controversial. It is believed ...
Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle
(1999)
The effects of chronic liver insufficiency resulting from end-to-side portacaval anastomosis (PCA) on glutamine synthetase (GS) activities, protein and gene expression were studied in brain, liver and skeletal muscle of ...
Hypothermia in acute liver failure
(2004)
The development of encephalopathy in patients with acute liver injury defines the occurrence of liver failure. The encephalopathy of acute liver failure is characterized by brain edema which manifests clinically as increased ...
Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease
(Wiley, 2024-04-29)
Hepatic encephalopathy (HE) is defined as decline in neurological function during
chronic liver disease (CLD). Alcohol is a major etiological factor in the pathogenesis of
fibrosis/cirrhosis and has also been documented ...