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An examination of semantic impairment in amnestic MCI and AD : What can we learn from verbal fluency?
(Oxford University Press, 2019-04-17)
Introduction
The Verbal Fluency Test (VF) is commonly used in neuropsychology. Some studies have demonstrated a marked impairment of semantic VF compared to phonemic VF in Alzheimer’s disease (AD). Since amnestic Mild ...
Subcortical amyloid relates to cortical morphology in cognitively normal individuals
(Springer, 2019-07-25)
Purpose Amyloid (Aβ) brain deposition can occur in cognitively normal individuals and is associated with cortical volume
abnormalities. Aβ-related volume changes are inconsistent across studies. Since volume is composed ...
Subcortical amyloid load is associated with shape and volume in cognitively normal individuals
Subcortical Aβ associates to morphometry
(Wiley, 2019-05-21)
Amyloid-beta (Aβ) deposition is one of the main hallmarks of Alzheimer’s disease. The
study assessed the associations between cortical and subcortical 11C-Pittsburgh Compound
B retention, namely in the hippocampus, ...
Amyloid burden and white matter hyperintensities mediate age-related cognitive differences
(Elsevier, 2019-08)
This study examined the additive versus synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMHs) across 7 cognitive domains in 104 cognitively normal older adults. It also measured the extent ...
A MEG study of the neural substrates of semantic processing in semantic variant primary progressive aphasia
(Taylor & Francis, 2019-07-01)
Despite a well-documented pattern of semantic memory (SM) impairment, the patterns of brain
activation during semantic processing in svPPA still remain poorly understood. The current study
aimed to investigate the neural ...
Education as a moderator of the relationship between episodic memory and amyloid load in normal aging
(Oxford University Press, 2019-10-23)
The current study explored whether education, a proxy of cognitive reserve, modifies the
association between episodic memory (EM) performance and βeta-amyloid load (Aβ), a biomarker
of Alzheimer’s disease, in a cohort ...