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Subcortical amyloid relates to cortical morphology in cognitively normal individuals
(Springer, 2019-07-25)
Purpose Amyloid (Aβ) brain deposition can occur in cognitively normal individuals and is associated with cortical volume
abnormalities. Aβ-related volume changes are inconsistent across studies. Since volume is composed ...
Subcortical amyloid load is associated with shape and volume in cognitively normal individuals
Subcortical Aβ associates to morphometry
(Wiley, 2019-05-21)
Amyloid-beta (Aβ) deposition is one of the main hallmarks of Alzheimer’s disease. The
study assessed the associations between cortical and subcortical 11C-Pittsburgh Compound
B retention, namely in the hippocampus, ...
Amyloid burden and white matter hyperintensities mediate age-related cognitive differences
(Elsevier, 2019-08)
This study examined the additive versus synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMHs) across 7 cognitive domains in 104 cognitively normal older adults. It also measured the extent ...
Education as a moderator of the relationship between episodic memory and amyloid load in normal aging
(Oxford University Press, 2019-10-23)
The current study explored whether education, a proxy of cognitive reserve, modifies the
association between episodic memory (EM) performance and βeta-amyloid load (Aβ), a biomarker
of Alzheimer’s disease, in a cohort ...