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Unified scaling of the structure and loading of nanoparticles formed via diffusion-limited coalescence
(American Chemical Society, 2018-04-30)
The present study establishes the scaling laws describing the structure of spherical nanoparticles formed by diffusion-limited coalescence. We produced drug-loaded nanoparticles from a poly(ethylene glycol)-poly(d,l-lactic ...
Effect of surface chemistry of polymeric nanoparticles on cutaneous penetration of cholecalciferol
(Elsevier, 2018-10-11)
We investigated the influence of nanoparticle (NP) surface composition on different aspects of skin delivery of a lipophilic drug: chemical stability, release and skin penetration. Cholecalciferol was chosen as a labile ...
Nanoparticle heterogeneity : an emerging structural parameter 2 influencing particle fate in biological media?
(Royal Society of Chemistry, 2018-11-27)
Drug nanocarriers’ surface chemistry is often presumed to be uniform. For instance, the polymer surface coverage and distribution of ligands on nanoparticles are described with averaged values obtained from quantification ...