Parcourir l'index des titres "Frontiers in cardiovascular medicine"

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  • Antiplatelet therapy for atherothrombotic disease in 2022 : from population to patient-centered approaches 

    Jourdi, Georges; Godier, Anne; Lordkipanidzé, Marie; Marquis-Gravel, Guillaume; Gaussem, Pascale (Frontiers Media, 2022-01-28)
    Antiplatelet agents, with aspirin and P2Y12 receptor antagonists as major key molecules, are currently the cornerstone of pharmacological treatment of atherothrombotic events including a variety of cardio- and cerebro-vascular as well as peripheral ...

  • Brain-derived neurotrophic factor mitigates the association between platelet dysfunction and cognitive impairment 

    Bélanger, Jean-Christophe; Bouchard, Véronique; Le Blanc, Jessica; Starnino, Louisia; Welman, Mélanie; Chabot-Blanchet, Malorie; Busseuil, David; Chertkow, Howard; D'Antono, Bianca; Lordkipanidzé, Marie (Frontiers media, 2021-09-07)
    Background: Platelet hyperactivity is deleterious in coronary artery disease (CAD), requiring lifelong antiplatelet therapy, and is associated with worse cognitive outcomes. Upon activation, platelets release Brain-Derived Neurotrophic Factor (BDNF), ...

  • Platelet function in aging 

    Le Blanc, Jessica; Lordkipanidzé, Marie (Frontiers Media, 2019-08-07)
    Aging is associated with an increased incidence of cardiovascular disease and thrombosis. Platelets play a major role in maintaining hemostasis and in thrombus formation, making them a key player in thrombotic disorders. Whereas it is well-known that ...