Parcourir Faculté de pharmacie par auteur·e "Elkin, Igor"
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Conception, synthèse et caractérisation de nouvelles macromolécules branchées biocompatibles pour encapsuler des principes actifs hydrophobes
Elkin, Igor (2014-05-01)La vectorisation des médicaments est une approche très prometteuse tant sur le plan médical qu’économique pour la livraison des substances actives ayant une faible biodisponibilité. Dans ce contexte, les polymères en étoile et les dendrimères, ... -
Drug-loaded nanocarriers : passive targeting and crossing of biological barriers
Rabanel, Jean-Michel; Aoun, Valery; Elkin, Igor; Mokhtar, Mohamed; Hildgen, Patrice (2012-12)Poor bioavailability and poor pharmacokinetic characteristics are some of the leading causes of drug development failure. Therefore, poorly-soluble drugs, fragile proteins or nucleic acid products may benefit from their encapsulation in nanosized ... -
Non-covalent formulation of active principles with dendrimers: current state-of-the-art and prospects for further development
Elkin, Igor; Banquy, Xavier; Barrett, Christopher J.; Hildgen, Patrice (Elsevier, 2017-09-06)During the last three decades, dendrimers, nano-sized highly-branched fractal-like symmetrical macromolecules, have been intensively studied as promising candidates for application as drug-delivery carriers. Among other important characteristics arising ...