Browsing Faculté de médecine – Thèses et mémoires by Subject "N3.35"
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The Independence of CXCR4’s Pathways, Gαi and β-Arrestin2, and Their Modulation by AMD3100 and TC14012
(2015-04-30)CXCR4, a chemokine receptor involved in metastasis and homing of hematopoietic stem cells, signals through two major pathways: Gαi and β-arrestin2. β-arrestin2 terminates G-protein signaling and targets the receptor to endocytosis. This project proposed ...