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dc.contributor.authorPalomino-Tapia, Victor A.
dc.contributor.authorMitevski, Darko
dc.contributor.authorInglis, Tom
dc.contributor.authorvan der Meer, Frank
dc.contributor.authorMartin, Emily
dc.contributor.authorBrash, Marina
dc.contributor.authorProvost, Chantale
dc.contributor.authorGagnon, Carl A.
dc.contributor.authorAbdul-Careem, Mohamed Faizal
dc.date.accessioned2020-10-02T19:01:18Z
dc.date.availableNO_RESTRICTIONfr
dc.date.available2020-10-02T19:01:18Z
dc.date.issued2020-09-28
dc.identifier.urihttp://hdl.handle.net/1866/24004
dc.publisherMDPIfr
dc.rightsCe document est mis à disposition selon les termes de la Licence Creative Commons Paternité 4.0 International. / This work is licensed under a Creative Commons Attribution 4.0 International License.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectChicken astrovirusfr
dc.subjectWhite chick syndromefr
dc.subjectRunting-stunting syndromefr
dc.subjectMolecular epidemiologyfr
dc.subjectWhole genome sequencingfr
dc.subjectRecombinationfr
dc.titleChicken astrovirus (CAstV) molecular studies reveal evidence of multiple past recombination events in sequences originated from clinical samples of white chick syndrome (WCS) in Western Canadafr
dc.typeArticlefr
dc.contributor.affiliationUniversité de Montréal. Faculté de médecine vétérinairefr
dc.identifier.doi10.3390/v12101096
dcterms.abstractIn this study, we aimed to molecularly characterize 14 whole genome sequences of chicken astrovirus (CAstV) isolated from samples obtained from white chick syndrome (WCS) outbreaks in Western Canada during the period of 2014–2019. Genome sequence comparisons showed all these sequences correspond to the novel Biv group from which no confirmed representatives were published in GenBank. Molecular recombination analyses using recombination detection software (i.e., RDP5 and SimPlot) and phylogenetic analyses suggest multiple past recombination events in open reading frame (ORF)1a, ORF1b, and ORF2. Our findings suggest that recombination events and the accumulation of point mutations may have contributed to the substantial genetic variation observed in CAstV and evidenced by the current seven antigenic sub-clusters hitherto described. This is the first paper that describes recombination events in CAstV following analysis of complete CAstV sequences originated in Canada.fr
dcterms.isPartOfurn:ISSN:1999-4915fr
dcterms.languageengfr
UdeM.ReferenceFournieParDeposantPalomino-Tapia V, Mitevski D, Inglis T, van der Meer F, Martin E, Brash M, Provost C, Gagnon CA, Abdul-Careem MF. Chicken Astrovirus (CAstV) Molecular Studies Reveal Evidence of Multiple Past Recombination Events in Sequences Originated from Clinical Samples of White Chick Syndrome (WCS) in Western Canada. Viruses. 2020 Sep 28;12(10):E1096. doi: 10.3390/v12101096. PMID: 32998356.fr
UdeM.VersionRioxxVersion publiée / Version of Recordfr
oaire.citationTitleVirusesfr
oaire.citationVolume12fr
oaire.citationIssue10fr


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Ce document est mis à disposition selon les termes de la Licence Creative Commons Paternité 4.0 International. / This work is licensed under a Creative Commons Attribution 4.0 International License.
RightsCe document est mis à disposition selon les termes de la Licence Creative Commons Paternité 4.0 International. / This work is licensed under a Creative Commons Attribution 4.0 International License.