Browsing Faculté des arts et des sciences – Département de physique - Travaux et publications by Author "Gaudreault, Roger"
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Corilagin and 1,3,6-Tri-O-galloyl-β -D-glucose : potential inhibitors of SARS-CoV-2 variants
Binette, Vincent; Côté, Sébastien; Haddad, Mohamed; Nguyen, Phuong Trang; Bélanger, Sébastien; Bourgault, Steve; Ramassamy, Charles; Gaudreault, Roger; Mousseau, Normand (2021-06-28)The COVID-19 disease caused by the virus SARS-CoV-2, first detected in December 2019, is still emerging through virus mutations. Although almost under control in some countries due to effective vaccines that are mitigating the worldwide pandemic, the ... -
Mitigating Alzheimer’s disease with natural polyphenols: a review
Gaudreault, Roger; Mousseau, Normand (Bentham Science, 2019-03-14)According to Alzheimer’s Disease International (ADI), nearly 50 million people worldwide were living with dementia in 2017, and this number is expected to triple by 2050. Despite years of research in this field, the root cause and mechanisms responsible ... -
Molecular interactions of tannic acid with proteins associated with SARS-CoV-2 infectivity
Haddad, Mohamed; Gaudreault, Roger; Sasseville, Gabriel; Nguyen, Phuong Trang; Wiebe, Hannah; Van De Ven, Theo; Bourgault, Steve; Mousseau, Normand; Ramassamy, Charles (MDPI, 2022-02-27)The overall impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on our society is unprecedented. The identification of small natural ligands that could prevent the entry and/or replication of the coronavirus remains a pertinent ... -
Polyphenol-peptide interactions in mitigation of Alzheimer’s disease : role of biosurface-induced aggregation
Gaudreault, Roger; Hervé, Vincent; Van De Ven, Theo; Mousseau, Normand; Ramassamy, Charles (IOS Press, 2021-05-08)Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder, responsible for nearly two-thirds of all dementia cases. In this review, we report the potential AD treatment strategies focusing on natural polyphenol molecules ...