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Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production
(2005)
The mechanism of endothelin-1 (ET-1)-induced nitric oxide (NO) production, MMP-1 production and MMP-13 production was investigated in human osteoarthritis chondrocytes. The cells were isolated from human articular cartilage ...