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Le libre accès pour les bibliothèques de la santé : des ressources à découvrir
(Institut universitaire de gériatrie de Montréal ; Hôpital général juif (Montréal, Québec), 2009-02-05)
Cette présentation s’adresse aux spécialistes de l’information du milieu de la santé et aborde les points suivants :
1. Le monde du « libre accès » : définitions et statistiques;
2. Utiliser les ressources en libre ...
Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum
(BioMed Central, 2007)
BACKGROUND: HIV-1 Vpu targets newly synthesized CD4 receptor for rapid degradation by a process reminiscent of endoplasmic reticulum (ER)-associated protein degradation (ERAD). Vpu is thought to act as an adaptor protein, ...
Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes
(Oxford University Press, 2008)
Proteolytic processing of the CUX1 transcription factor generates an isoform, p110 that accelerates entry into S phase. To identify targets of p110 CUX1 that are involved in cell cycle progression, we performed genome-wide ...
New pandemics: HIV and AIDS, HCV and chronic hepatitis, Influenza virus and flu
(BioMed Central, 2007)
New pandemics are a serious threat to the health of the entire world. They are essentially of viral origin and spread at large speed. A meeting on this topic was held in Lyon, France, within the XIXth Jacques Cartier ...
Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by {beta}-catenin signaling
(Public Library of Science, 2008)
BACKGROUND: The role of ss-catenin signaling in mesodermal lineage formation and differentiation has been elusive. METHODOLOGY: To define the role of ss-catenin signaling in these processes, we used a Dermo1(Twist2)(Cre/+) ...
Rehabilitation needs for older adults with stroke living at home: perceptions of four populations
(2007-08-13)
BACKGROUND: Many people who have suffered a stroke require rehabilitation to help them resume their previous activities and roles in their own environment, but only some of them receive inpatient or even outpatient ...
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model
(2009)
BACKGROUND: The secretory basic amino acid-specific proprotein convertases (PCs) have often been associated with cancer/metastasis. By controlling the cleavage of cancer-associated proteins, PCs play key roles in multiple ...
Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure
(2007-12)
We previously demonstrated in pigs with acute liver failure (ALF) that albumin dialysis using the molecular adsorbents recirculating system (MARS) attenuated a rise in intracranial pressure (ICP). This was independent of ...
L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure
(2009-07)
Hyperammonemia is a feature of acute liver failure (ALF), which is associated with increased intracranial pressure (ICP) and brain herniation. We hypothesized that a combination of L-ornithine and phenylacetate (OP) would ...
Limited capacity for ammonia removal by brain in chronic liver failure: potential role of nitric oxide
(2005-12)
Chronic liver failure leads to hyperammonemia and consequently increased brain ammonia concentrations, resulting in hepatic encephalopathy. When the liver fails to regulate ammonia concentrations, the brain, devoid of a ...