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The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure : a nested case–control study
(Springer, 2017)
Background: Acetaminophen (APAP)-induced acute liver failure (ALF) is associated with signifcant mortality due to
intracranial hypertension (ICH), a result of cerebral edema (CE) and astrocyte swelling. Brain-type fatty ...
Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile-duct ligated rats
(Wiley, 2022-06-30)
Hepatic encephalopathy (HE) is a debilitating neurological complication of chronic liver disease (CLD). Hyperammonemia plays an important role in HE’s pathogenesis, acting synergistically with systemic oxidative stress. ...
Plasmatic osmolality and hepatic encephalopathy : a new player on the field?
(Wiley, 2020-08-31)
Nutritional education strategies for patients with cirrhosis : a narrative review
(Elsevier, 2023-06-30)
Background
Patients with cirrhosis suffer from many complications, including malnutrition, which must be managed promptly and effectively by the healthcare team. Educating patients about their medical condition, the risk ...
Elevated serum liver-type fatty acid binding protein levels in non-acetaminophen acute liver failure patients with organ dysfunction.
(Springer, 2020-03-03)
Liver-type fatty acid binding protein (FABP1) has previously been
demonstrated to improve prognostic discrimination in acetaminophen (APAP)-induced
ALF but has not been investigated in other etiologies of ...
Bile‐duct ligation renders the brain susceptible to hypotension induced neuronal degeneration : implications of ammonia
Hypotension in hepatic encephalopathy
(Wiley, 2020-12-31)
Hepatic encephalopathy (HE) is a debilitating neurological complication of cirrhosis. By definition, HE is considered a reversible disorder, and therefore HE should resolve following liver transplantation (LT). However, ...
Heretical thoughts into hepatic encephalopathy
(Elsevier & European Association for the Study of the Liver, 2022-03-27)
Clinical progress in the development of new diagnostic modalities and therapeutic strategies for the management of patients with hepatic encephalopathy has lagged behind the vast knowledge that has been generated from basic ...
Amino acids, ammonia, and hepatic encephalopathy
(Elsevier, 2022-04-30)
Hepatic encephalopathy (HE) is a decline in brain function arising due to liver insufficiency. The liver's diminished capacity to clear ammonia, and the subsequent accumulation of it, is highly implicated in pathogenesis ...
Renal dysfunction independently predicts muscle mass loss in patients following liver transplantation
(University of Toronto Press, 2022-05-02)
Liver transplantation (LT) is the only curative treatment for cirrhosis. However, the presence of
complications can impact outcomes following LT. Sarcopenia, or muscle mass loss, is highly prevalent in patients with
cirrhosis ...
Brain edema : a valid endpoint for measuring hepatic encephalopathy?
(2016-06)
Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease. This metabolic neuropsychiatric syndrome involves a spectrum of ...