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Mild hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects
(2002-12)
Mild hypothermia (32 degrees C-35 degrees C) reduces intracranial pressure in patients with acute liver failure and may offer an effective adjunct therapy in the management of these patients. Studies in experimental animals ...
Hypothermia in acute liver failure
(2004)
The development of encephalopathy in patients with acute liver injury defines the occurrence of liver failure. The encephalopathy of acute liver failure is characterized by brain edema which manifests clinically as increased ...
Systemic and regional hemodynamics in pigs with acute liver failure and the effect of albumin dialysis
(2006)
OBJECTIVE: Acute liver failure (ALF) is haemodynamically characterized by a hyperdynamic circulation. The aims of this study were to investigate the systemic and regional haemodynamics in ALF, to measure changes in nitric ...
Contractile response of femoral arteries in pigs with acute liver failure
(2004)
BACKGROUND: Acute liver failure (ALF) is characterized haemodynamically by a progressive hyperdynamic circulation. The pathophysiological mechanism is unknown, but impaired contractility of vascular smooth muscle may play ...
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia
(2004)
The principal cause of mortality in patients with acute liver failure (ALF) is brain herniation resulting from intracranial hypertension caused by a progressive increase of brain water. In the present study, ex vivo ...