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The social dynamics involved in recovery and return to sport following a sport-related concussion : a study of three athlete-teammate-coach triads
(Elsevier, 2020-10-09)
An athlete's connection to their team and team members is an important part of their sport experience. However, researchers currently know little about the nature of these social dynamics with respect to concussed athletes. ...
Hepatic encephalopathy : novel insights into classification, pathophysiology and therapy
(Elsevier, 2020-10-21)
Hepatic encephalopathy (HE) is a frequent and serious complication of both chronic liver disease and acute liver failure. HE manifests as a wide spectrum of neuropsychiatric abnormalities, from subclinical changes (mild ...
Distinct cognitive and discriminative stimulus effects of ketamine enantiomers in rats
(Elsevier, 2020-08-03)
Although (S)-ketamine was approved for use in treatment-resistant depression in 2019, new preclinical findings suggest that (R)-ketamine might produce better efficacy and tolerability relative to (S)-ketamine. Here we ...
French translation and validation of the Synkinesis Assessment Questionnaire
French translation and validation of SAQ questionnaire
(Cambridge University Press, 2020-09-22)
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma
(Nature Research, 2020-07-20)
The mechanisms generating cancer-initiating mutations are not well understood. Sonic hedgehog (SHH) pathway activation is frequent in medulloblastoma (MB), with PTCH1 mutations being a common initiating event. Here we ...
Autophagy, tissue repair, and fibrosis: a delicate balance
(Elsevier, 2021-01-14)
Tissue repair and fibrosis, an abnormal form of repair, occur in most human organs in response to injury or inflammation. Fibroblasts play a major role in the normal repair process by differentiating into myofibroblasts ...
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats
(Lippincott, Williams & Wilkins, 2020-07-06)
BACKGROUND
Multiorgan failure is a consequence of severe ischemia-reperfusion injury after traumatic hemorrhagic shock (HS), a major cause of mortality in trauma patients. Circulating uric acid (UA), released from cell ...
Computationally efficient model to predict the deformations of a cellular foot orthotic
(Elsevier, 2022-04-21)
Background
Foot orthotics (FOs) are frequently prescribed to provide comfortable walking for patients. Finite element (FE) simulation and 3D printing pave the way to analyse, optimize and fabricate functionally graded ...
Metabotropic group II glutamate receptors in the basolateral amygdala mediate cue-triggered increases in incentive motivation
(Springer, 2021-07-05)
Rationale: Reward-associated cues can trigger incentive motivation for reward and invigorate reward-seeking behaviour via Pavlovian-to-instrumental transfer (PIT). Glutamate signaling within the basolateral amygdala (BLA) ...