• Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents 

    Büchel, Christian; Peters, Jan; Banaschewski, Tobias; Bokde, Arun W. L.; Bromberg, Uli; Conrod, Patricia; Flor, Herta; Papadopoulos Orfanos, Dimitri; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Walter, Henrik; Ittermann, Bernd; Mann, Karl; Martinot, Jean-Luc; Paillère-Martinot, Marie-Laure; Nees, Frauke; Paus, Tomáš; Pausova, Zdenka; Poustka, Luise; Rietschel, Marcella; Robbins, Trevor W.; Smolka, Michael N.; Gallinat, Jürgen; Schumann, Gunter; Knutson, Brian; Imagen Consortium (Nature Research, 2017-02-21)
    Novelty-seeking tendencies in adolescents may promote innovation as well as problematic impulsive behaviour, including drug abuse. Previous research has not clarified whether neural hyper- or hypo-responsiveness to anticipated rewards promotes vulnerability ...
  • Early cannabis use, polygenic risk score for schizophrenia and brain maturation in adolescence 

    French, Leon; Gray, Courtney; Leonard, Gabriel; Perron, Michel; Pike, Bruce; Richer, Louis; Séguin, Jean; Veillette, Suzanne; Evans, John; Artiges, Eric; Banaschewski, Tobias; Bokde, Arun W. L.; Bromberg, Uli; Bruehl, Ruediger; Büchel, Christian; Cattrell, Anna; Conrod, Patricia; Flor, Herta; Frouin, Vincent; Gallinat, Jürgen; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Lemaître, Hervé; Martinot, Jean-Luc; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Pangelinan, Melissa Marie; Poustka, Luise; Rietschel, Marcella; Smolka, Michael N.; Walter, Henrik; Whelan, Robert; Timpson, Nic J.; Schumann, Gunter; Smith, George Davey; Smith, George Davey; Pausova, Zdenka; Paus, Tomáš (American Medical Association, 2015-10)
    IMPORTANCE: Cannabis use during adolescence is known to increase the risk for schizophrenia in men. Sex differences in the dynamics of brain maturation during adolescence may be of particular importance with regard to vulnerability of the male brain ...
  • Inattention and reaction time variability are linked to ventromedial prefrontal volume in adolescents 

    Albaugh, Matthew D.; Orr, Catherine; Chaarani, Bader; Althoff, Robert R.; Allgaier, Nicholas; D’Alberto, Nicholas; Hudson, Kelsey; Mackey, Scott; Spechler, Philip A.; Banaschewski, Tobias; Brühl, Rüdiger; Bokde, Arun W. L.; Bromberg, Uli; Büchel, Christian; Cattrell, Anna; Conrod, Patricia; Desrivières, Sylvane; Flor, Herta; Frouin, Vincent; Gallinat, Jürgen; Goodman, Robert; Gowland, Penny; Grimmer, Yvonne; Heinz, Andreas; Kappel, Viola; Martinot, Jean-Luc; Paillère-Martinot, Marie-Laure; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Penttiä, Jani; Poustka, Luise; Paus, Tomáš; Smolka, Michael N.; Struve, Maren; Walter, Henrik; Whelan, Robert; Schumann, Gunter; Garavan, Hugh; Potter, Alexandra S. (Elsevier, 2017-01-13)
    Background Neuroimaging studies of attention-deficit/hyperactivity disorder (ADHD) have most commonly reported volumetric abnormalities in the basal ganglia, cerebellum, and prefrontal cortices. Few studies have examined the relationship between ADHD ...
  • Pubertal maturation and sex effects on the default-mode network connectivity implicated in mood dysregulation 

    Ernst, Monique; Benson, Brenda; Artiges, Eric; Gorka, Adam X.; Lemaître, Hervé; Lago, Tiffany; Miranda, Ruben; Banaschewski, Tobias; Bokde, Arun W. L.; Bromberg, Uli; Brühl, Rüdiger; Büchel, Christian; Cattrell, Anna; Conrod, Patricia; Desrivières, Sylvane; Fadai, Tahmine; Flor, Herta; Grigis, Antoine; Gallinat, Jürgen; Garavan, Hugh; Gowland, Penny; Grimmer, Yvonne; Heinz, Andreas; Kappel, Viola; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Penttilä, Jani; Poustka, Luise; Smolka, Michael N.; Stringaris, Argyris; Struve, Maren; Van Noort, Betteke M.; Walter, Henrik; Whelan, Robert; Schumann, Gunter; Grillon, Christian; Paillère-Martinot, Marie-Laure; Martinot, Jean-Luc; IMAGEN Consortium (Springer Nature, 2019-02-25)
    This study examines the effects of puberty and sex on the intrinsic functional connectivity (iFC) of brain networks, with a focus on the default-mode network (DMN). Consistently implicated in depressive disorders, the DMN’s function may interact with ...