Browsing Faculté de médecine by Author "Orlov, Serguei"
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HCO3 dependent impact of Na+,K+, 2Cl cotransport in vascular smooth muscle excitation-contraction coupling
Koltsova, Svetlana V.; Luneva, Oksana G.; Lavoie, Julie; Tremblay, Johanne; Maksimov, Georgy V.; Hamet, Pavel; Orlov, Serguei (Krager, 2009)In smooth muscles, inhibition of Na(+),K(+),2Cl(-) cotransport (NKCC) by bumetanide decreased intracellular Cl(-) content ([Cl(-)](i)) and suppressed the contractions triggered by diverse stimuli. This study examines whether or not bicarbonate, a ...