Parcourir Faculté de médecine par auteur·e "Kafando, Alexis"

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  • Caractérisation moléculaire et phylogénétique de l’enveloppe du VIH-1 transmis/fondateur 

    Kafando, Alexis (2020-03-18)
    Vaincre efficacement l’infection par le VIH nécessite non seulement de raffiner davantage les traitements antirétroviraux, mais aussi de déployer des moyens de prévention à large échelle afin de stopper la propagation de la maladie. Il s’agit en effet ...

  • HIV-1 envelope glycoprotein amino acids signatures associated with clade B transmitted/founder and recent viruses 

    Kafando, Alexis; Martineau, Christine; El-Far, Mohamed; Fournier, Eric; Doualla-Bell, Florence; Serhir, Bouchra; Kazienga, Adama; Sangaré, Mohamed Ndongo; Sylla, Mohamed; Chamberland, Annie; Charest, Hugues; Tremblay, Cécile (MDPI, 2019-11-01)
    Background: HIV-1 transmitted/founder viruses (TF) are selected during the acute phase of infection from a multitude of virions present during transmission. They possess the capacity to establish infection and viral dissemination in a new host. Deciphering ...

  • HIV-1 envelope sequence-based diversity measures for identifying recent infections 

    Kafando, Alexis; Fournier, Eric; Serhir, Bouchra; Martineau, Christine; Doualla-Bell, Florence; Sangaré, Mohamed Ndongo; Sylla, Mohamed; Chamberland, Annie; El-Far, Mohamed; Charest, Hugues; Tremblay, Cécile (Public Library of Science, 2017-12-28)
    Identifying recent HIV-1 infections is crucial for monitoring HIV-1 incidence and optimizing public health prevention efforts. To identify recent HIV-1 infections, we evaluated and compared the performance of 4 sequence-based diversity measures including ...

  • A short-term assessment of nascent HIV-1 transmission clusters among newly diagnosed individuals using envelope sequence-based phylogenetic analyses 

    Kafando, Alexis; Serhir, Bouchra; Doualla-Bell, Florence; Fournier, Eric; Sangaré, Mohamed Ndongo; Martineau, Christine; Sylla, Mohamed; Chamberland, Annie; El-Far, Mohamed; Charest, Hugues; Tremblay, Cécile (Mary Ann Liebert, 2019-10-01)
    The identification of transmission clusters (TCs) of HIV-1 using phylogenetic analyses can provide insights into viral transmission network and help improve prevention strategies. We compared the use of partial HIV-1 envelope fragment of 1,070 bp ...