Browsing Titles index "Frontiers in immunology"

Now showing items 1-5 of 5

  • Immunoregulatory CD4-CD8- T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer 

    Hillhouse, Erin; Delisle, Jean-Sébastien; Lesage, Sylvie (Frontiers media, 2013-01-13)
    A central objective in organ transplantation and the treatment or prevention of autoimmune disease is the achievement of antigen-specific immune tolerance. An additional challenge in bone marrow transplantation for the treatment of hematological ...

  • The NOD mouse beyond autoimmune diabetes 

    Aubin, Anne-Marie; Lombard-Vadnais, Félix; Collin, Roxanne; Aliesky, Holly A.; McLachlan, Sandra M.; Lesage, Sylvie (Frontiers Media, 2022-04-29)
    Autoimmune diabetes arises spontaneously in Non-Obese Diabetic (NOD) mice, and the pathophysiology of this disease shares many similarities with human type 1 diabetes. Since its generation in 1980, the NOD mouse, derived from the Cataract Shinogi ...

  • Restoring T cell homeostasis after allogeneic stem cell transplantation; principal limitations and future challenges 

    Mohamed Moutuou, Moutuaata; Pagé, Gabriel; Zaid, Intesar; Lesage, Sylvie; Guimond, Martin (Frontiers Media, 2018-06-18)
    For several leukemia patients, allogeneic stem cell transplantation (allogeneic-SCT) is the unique therapeutic modality that could potentially cure their disease. Despite significant progress made in clinical management of allogeneic-SCT, acute ...

  • Revisiting the prominent anti-tumoral potential of pre-mNK cells 

    Guimont-Desrochers, Fanny; Lesage, Sylvie (Frontiers Media, 2013-12-11)
    Interferon-producing killer dendritic cells (IKDC) were first described for their outstanding anti-tumoral properties.The “IKDC” terminology implied the description of a novel DC subset and initiated a debate on their cellular lineage origin.This ...

  • Upregulated IL-32 expression and reduced gut short chain fatty acid caproic acid in people living with HIV with subclinical atherosclerosis 

    El-Far, Mohamed; Durand, Madeleine; Turcotte, Isabelle; Larouche-Anctil, Etienne; Sylla, Mohamed; Zaidan, Sarah; Chartrand-Lefebvre, Carl; Bunet, Rémi; Ramani, Hardik; Sadouni, Manel; Boldeanu, Irina; Chamberland, Annie; Lesage, Sylvie; Baril, Jean-Guy; Trottier, Benoit; Thomas, Réjean; Gonzalez, Emmanuel; Filali-Mouhim, Ali; Goulet, Jean-Philippe; Martinson, Jeffrey A.; Kassaye, Seble; Karim, Roksana; Kizer, Jorge R.; French, Audrey L.; Gange, Stephen J.; Ancuta, Petronela; Routy, Jean-Pierre; Hanna, David B.; Kaplan, Robert C.; Chomont, Nicolas; Landay, Alan L.; Tremblay, Cécile (Frontiers Media, 2021-04-15)
    Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) are still at higher risk for cardiovascular diseases (CVDs) that are mediated by chronic inflammation. Identification of novel inflammatory mediators with the inherent ...