Browsing Faculté de médecine by Author "Roy, Bibhuti Bhusan"
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Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment
Dubé, Mathieu; Roy, Bibhuti Bhusan; Guiot-Guillain, Pierre; Binette, Julie; Mercier, Johanne; Chiasson, Antoine; Cohen, Éric A. (2010)The Vpu accessory protein promotes HIV-1 release by counteracting Tetherin/BST-2, an interferon-regulated restriction factor, which retains virions at the cell-surface. Recent reports proposed beta-TrCP-dependent proteasomal and/or endo-lysosomal ...