Browsing Faculté de médecine by Author "Mukhopadhyay, Shubhashish M. M."
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Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters
Chi, Gamma; Ebenhoch, Rebecca; Man, Henry; Tang, Haiping; Tremblay, Laurence; Reggiano, Gabriella; Qiu, Xingyu; Bohstedt, Tina; Liko, Idlir; Almeida, Fernando G.; Garneau, Alexandre; Wang, Dong; McKinley, Gavin; Moreau, Christophe P.; Bountra, Kiran D.; Abrusci, Patrizia; Mukhopadhyay, Shubhashish M. M.; Fernandez-Cid, Alejandra; Slimani, Samira; Lavoie, Julie; Burgess-Brown, Nicola A.; Tehan, Ben; DiMaio, Frank; Jazayeri, Ali; Isenring, Paul; Robinson, Carol V.; Durr, Katharina L. (2021-05-25)Potassium-coupled chloride transporters (KCCs) play crucial roles in regulating cell volume and intracellular chloride concentration. They are characteristically inhibited under isotonic conditions via phospho-regulatory sites located within the ...