dc.contributor.author | Palomino-Tapia, Victor A. | |
dc.contributor.author | Mitevski, Darko | |
dc.contributor.author | Inglis, Tom | |
dc.contributor.author | Van der Meer, Frank | |
dc.contributor.author | Martin, Emily | |
dc.contributor.author | Brash, Marina | |
dc.contributor.author | Provost, Chantale | |
dc.contributor.author | Gagnon, Carl A. | |
dc.contributor.author | Abdul-Careem, Mohamed Faizal | |
dc.date.accessioned | 2020-10-02T19:01:18Z | |
dc.date.available | NO_RESTRICTION | fr |
dc.date.available | 2020-10-02T19:01:18Z | |
dc.date.issued | 2020-09-28 | |
dc.identifier.uri | http://hdl.handle.net/1866/24004 | |
dc.publisher | MDPI | fr |
dc.rights | Ce document est mis à disposition selon les termes de la Licence Creative Commons Paternité 4.0 International. / This work is licensed under a Creative Commons Attribution 4.0 International License. | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Chicken astrovirus | fr |
dc.subject | White chick syndrome | fr |
dc.subject | Runting-stunting syndrome | fr |
dc.subject | Molecular epidemiology | fr |
dc.subject | Whole genome sequencing | fr |
dc.subject | Recombination | fr |
dc.title | Chicken astrovirus (CAstV) molecular studies reveal evidence of multiple past recombination events in sequences originated from clinical
samples of white chick syndrome (WCS) in Western Canada | fr |
dc.type | Article | fr |
dc.contributor.affiliation | Université de Montréal. Faculté de médecine vétérinaire | fr |
dc.identifier.doi | 10.3390/v12101096 | |
dcterms.abstract | In this study, we aimed to molecularly characterize 14 whole genome sequences of chicken
astrovirus (CAstV) isolated from samples obtained from white chick syndrome (WCS) outbreaks
in Western Canada during the period of 2014–2019. Genome sequence comparisons showed all
these sequences correspond to the novel Biv group from which no confirmed representatives were
published in GenBank. Molecular recombination analyses using recombination detection software
(i.e., RDP5 and SimPlot) and phylogenetic analyses suggest multiple past recombination events in
open reading frame (ORF)1a, ORF1b, and ORF2. Our findings suggest that recombination events
and the accumulation of point mutations may have contributed to the substantial genetic variation
observed in CAstV and evidenced by the current seven antigenic sub-clusters hitherto described.
This is the first paper that describes recombination events in CAstV following analysis of complete
CAstV sequences originated in Canada. | fr |
dcterms.isPartOf | urn:ISSN:1999-4915 | fr |
dcterms.language | eng | fr |
UdeM.ReferenceFournieParDeposant | Palomino-Tapia V, Mitevski D, Inglis T, van der Meer F, Martin E, Brash M, Provost C, Gagnon CA, Abdul-Careem MF. Chicken Astrovirus (CAstV) Molecular Studies Reveal Evidence of Multiple Past Recombination Events in Sequences Originated from Clinical Samples of White Chick Syndrome (WCS) in Western Canada. Viruses. 2020 Sep 28;12(10):E1096. doi: 10.3390/v12101096. PMID: 32998356. | fr |
UdeM.VersionRioxx | Version publiée / Version of Record | fr |
oaire.citationTitle | Viruses | fr |
oaire.citationVolume | 12 | fr |
oaire.citationIssue | 10 | fr |