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Brain edema in acute liver failure and chronic liver disease: Similarities and differences
(2013)
Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome that typically develops as a result of acute liver failure or chronic liver disease. Brain edema is a common feature associated with HE. In acute liver ...
Oxidative stress: a systemic factor implicated in the pathogenesis of hepatic encephalopathy
(2013)
Although ammonia is considered the main factor involved in the pathogenesis of hepatic encephalopathy (HE), it correlates well with the severity of HE in acute liver failure, but not in chronic liver disease. Oxidative ...
Neuropathological changes in the brain of pigs with acute liver failure
(2010-08)
Abstract Objective. Cerebral edema is a serious complication of acute liver failure (ALF), which may lead to intracranial hypertension and death. An accepted tenet has been that the blood-brain barrier is intact and that ...
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure
(2012-04)
Chronic liver failure leads to hyperammonemia, a central component in the pathogenesis of hepatic encephalopathy (HE); however, a correlation between blood ammonia levels and HE severity remains controversial. It is believed ...