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Subcortical amyloid load is associated with shape and volume in cognitively normal individuals
Subcortical Aβ associates to morphometry
Amyloid-beta (Aβ) deposition is one of the main hallmarks of Alzheimer’s disease. The study assessed the associations between cortical and subcortical 11C-Pittsburgh Compound B retention, namely in the hippocampus, ...
Subcortical amyloid relates to cortical morphology in cognitively normal individuals
Purpose Amyloid (Aβ) brain deposition can occur in cognitively normal individuals and is associated with cortical volume abnormalities. Aβ-related volume changes are inconsistent across studies. Since volume is composed ...
A MEG study of the neural substrates of semantic processing in semantic variant primary progressive aphasia
(Taylor & Francis, 2019-07-01)
Despite a well-documented pattern of semantic memory (SM) impairment, the patterns of brain activation during semantic processing in svPPA still remain poorly understood. The current study aimed to investigate the neural ...
Education as a moderator of the relationship between episodic memory and amyloid load in normal aging
(Oxford University Press, 2019-10-23)
The current study explored whether education, a proxy of cognitive reserve, modifies the association between episodic memory (EM) performance and βeta-amyloid load (Aβ), a biomarker of Alzheimer’s disease, in a cohort ...