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Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults
Gray matter increases with obstructive sleep apnea
(American Thoracic Society, 2017-06-01)
Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations,
and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly
assessed with neuroimaging.
Objectives: ...
Sleep spindles are resilient to extensive white matter deterioration
(Oxford University Press, 2020-06-13)
Sleep spindles are an essential part of non-rapid eye movement sleep, notably involved in sleep consolidation, cognition, learning
and memory. These oscillatory waves depend on an interaction loop between the thalamus and ...
Waking EEG functional connectivity in middle-aged and older adults with obstructive sleep apnea
(Elsevier, 2020-06-14)
Objectives: The present study aimed at investigating changes in waking electroencephalography
(EEG), most specifically regarding spectral power and functional connectivity, in middle-aged and
older adults with OSA. We ...
Obstructive sleep apnea and the risk of cognitive decline in older adults
(American Thoracic Society, 2019-01-15)
Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure ...
Brain white matter damage and its association with neuronal synchrony during sleep
(Oxford University Press, 2019-01-28)
The restorative function of sleep partly relies on its ability to deeply synchronize cerebral networks to create large slow oscillations observable with EEG. However, whether a brain can properly synchronize and produce a ...
Obstructive sleep apnea during REM sleep and daytime cerebral functioning : a regional cerebral blood flow study using high-resolution SPECT
(SAGE, 2018-11-22)
Obstructive sleep apnea (OSA) predominantly during rapid eye movement (REM) sleep may have impacts on brain health, even in milder OSA cases. Here, we evaluated whether REM sleep OSA is associated with abnormal daytime ...
Visual fixation in the intensive care unit: a strong predictor of post-traumatic amnesia and long-term recovery after moderate-to-severe traumatic brain injury
Visual fixation in the ICU
(Lippincott, Williams & Wilkins, 2016-12-01)
Objective: We examined whether visual fixation at 24h of intensive care unit (ICU) admission is superior to the initial Glasgow Coma Scale (GCS) score to predict PTA duration and long-term TBI recovery. Design: Two-phase ...
Association between waking electroencephalography and cognitive event-related potentials in patients with obstructive sleep apnea
EEG and ERP in OSA
(Elsevier, 2013)
Objective: Abnormal event-related potentials (ERP) and slowing of the waking
electroencephalographic (EEG) activity have been reported in patients with obstructive
sleep apneas (OSA). This study aimed at evaluating whether ...
Biomarkers of dementia in obstructive sleep apnea
(Elsevier, 2018-08-13)
Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep
apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due
to obstructive ...
Regional cerebral blood flow during wakeful rest in older subjects with mild to severe obstructive sleep apnea
Cerebral perfusion in OSA
(Oxford University Press, 2015)
Objectives: To evaluate changes in regional cerebral blood flow (rCBF) during wakeful rest in older
subjects with mild to severe obstructive sleep apnea (OSA) and healthy controls, and to identify
markers of OSA severity ...