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dc.contributor.authorKristiansen, Kai
dc.contributor.authorDonaldson, Stephen
dc.contributor.authorBerkson, Zachariah J.
dc.contributor.authorScott, Jeffrey
dc.contributor.authorSu, Rongxin
dc.contributor.authorBanquy, Xavier
dc.contributor.authorDong Woog, Lee
dc.contributor.authorde Aguiar, Hilton B.
dc.contributor.authorMcGraw, Joshua
dc.contributor.authorDegen, George D.
dc.contributor.authorIsraelachvili, Jacob N.
dc.date.accessioned2020-03-27T18:18:31Z
dc.date.availableMONTHS_WITHHELD:12fr
dc.date.available2020-03-27T18:18:31Z
dc.date.issued2019-07-30
dc.identifier.urihttp://hdl.handle.net/1866/23153
dc.publisherAmerican Chemical Societyfr
dc.titleA multi-modal miniature surface forces apparatus (µSFA) for interfacial science measurementsfr
dc.typeArticlefr
dc.contributor.affiliationUniversité de Montréal. Faculté de pharmaciefr
dc.identifier.doi10.1021/acs.langmuir.9b01808
dcterms.abstractAdvances in the research of intermolecular and surface interactions result from the development of new and improved measurement techniques and combinations of existing techniques. Here, we present a new miniature version of the Surface Force Apparatus – the micro-SFA (µSFA) – that has been designed for ease of use and multi-modal capabilities with retention of the capabilities of other SFA models including accurate measurement of surface separation distance and physical characterization of dynamic and static physical forces (i.e., normal, shear, and friction) and interactions (e.g., van der Waals, electrostatic, hydrophobic, steric, bio-specific). The small physical size of the µSFA makes it portable and suitable for integration into commercially available optical and fluorescence light microscopes, as demonstrated here. The large white-light optical path entry and exit ports make it ideal for concurrent force measurements and spectroscopy studies. Examples of the use of the µSFA in combination with surface plasmon resonance (SPR) and Raman spectroscopy measurements are presented. Due to the short working distance constraints associated with Raman spectroscopy, a new interferometric technique was developed and applied for calculating the inter-surface separation distance based on Newton’s Rings. The introduction of the µSFA will mark a transition in SFA usage from primarily physical characterization to physical characterization with combined and concurrent in situ chemical and biological characterization, including (but not limited to) adsorption of selected molecules, determination of surface species and morphology, and (bio-)molecular binding kinetics.fr
dcterms.languageengfr
UdeM.ReferenceFournieParDeposantA Multi-Modal Miniature Surface Forces Apparatus (µSFA) for Interfacial Science Measurements Kai Kristiansen, Stephen Donaldson, Zachariah J. Berkson, Jeffrey Scott§, Rongxin Su, Xavier Banquy, Dong Woog Lee, Hilton B. de Aguiar, Joshua McGraw‖, George D. Degen, and Jacob N. Israelachvili Langmuir 35, 48, 15500-15514, 2019fr
UdeM.VersionRioxxVersion originale de l'auteur / Author's Originalfr
oaire.citationTitleLangmuir
oaire.citationVolume35
oaire.citationIssue48
oaire.citationStartPage15433
oaire.citationEndPage16070


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