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dc.contributor.authorPineault, Jessica
dc.contributor.authorJolicoeur, Pierre
dc.contributor.authorGrimault, Stephan
dc.contributor.authorLacombe, Jacinthe
dc.contributor.authorBrambati, Simona Maria
dc.contributor.authorBier, Nathalie
dc.contributor.authorChayer, Céline
dc.contributor.authorJoubert, Sven
dc.date.accessioned2019-09-10T13:41:45Z
dc.date.availableMONTHS_WITHHELD:12fr
dc.date.available2019-09-10T13:41:45Z
dc.date.issued2019-07-01
dc.identifier.urihttp://hdl.handle.net/1866/22358
dc.publisherTaylor & Francisfr
dc.subjectSemantic memoryfr
dc.subjectSingle-case studyfr
dc.subjectSemantic variant primary progressive aphasiafr
dc.subjectFunctional neuroimagingfr
dc.titleA MEG study of the neural substrates of semantic processing in semantic variant primary progressive aphasiafr
dc.typeArticlefr
dc.contributor.affiliationUniversité de Montréal. Faculté des arts et des sciences. Département de psychologiefr
dc.identifier.doi10.1080/13554794.2019.1631853
dcterms.abstractDespite a well-documented pattern of semantic memory (SM) impairment, the patterns of brain activation during semantic processing in svPPA still remain poorly understood. The current study aimed to investigate the neural substrates of residual semantic processing in the context of this significant but selective SM impairment, through the case study of one svPPA patient. One svPPA patient (EC) and six elderly controls carried out a general-level semantic categorization task (biological and manufactured objects) while their brain activity was recorded using magnetoencephalography (MEG). Despite similar behavioral performance, EC showed hyperactivation of the left inferior temporal gyrus (ITG) and right anterior temporal lobe (ATL) relative to controls. This suggests that periatrophic regions within the ATL region may support preserved semantic abilities in svPPA. These results thus contribute to our understanding of the brain regions which are recruited to compensate for bilateral atrophy of the ATL and ensure residual semantic processing in svPPA.fr
dcterms.bibliographicCitationNeurocase ; vol. 25, no 3-4, p. 118-129fr
dcterms.isPartOfurn:ISSN:1355-4794fr
dcterms.isPartOfurn:ISSN:1465-3656fr
dcterms.languageengfr
UdeM.ReferenceFournieParDeposantPineault J, Jolicœur P, Grimault S, Lacombe J, Brambati SM, Bier N, Chayer C, Joubert S. A MEG study of the neural substrates of semantic processing in semantic variant primary progressive aphasia. Neurocase. 25(3-4):118-129 (2019).fr
UdeM.VersionRioxxVersion acceptée / Accepted Manuscriptfr


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