Liens externes
  • Directories
  • Faculties
  • Libraries
  • Campus maps
  • Sites A to Z
  • My UdeM
    • Mon portail UdeM
    • My email
    • StudiUM
Dessin du pavillon Roger Gaudry/Sketch of Roger Gaudry Building
University Home pageUniversity Home pageUniversity Home page
Papyrus : Institutional Repository
Papyrus
Institutional Repository
Papyrus
    • français
    • English
  • English 
    • français
    • English
  • Login
  • English 
    • français
    • English
  • Login
View Item 
  •   Home
  • Faculté des arts et des sciences
  • FAS - École de psychoéducation
  • FAS – École de psychoéducation – Travaux et publications
  • View Item
  •   Home
  • Faculté des arts et des sciences
  • FAS - École de psychoéducation
  • FAS – École de psychoéducation – Travaux et publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

My Account

To submit an item or subscribe to email alerts.
Login
New user?

Browse

All of PapyrusCommunities and CollectionsTitlesIssue DatesAuthorsAdvisorsSubjectsDisciplinesAffiliationTitles indexThis CollectionTitlesIssue DatesAuthorsAdvisorsSubjectsDisciplinesAffiliationTitles index

Statistics

View Usage Statistics
Show metadata
Permalink: http://hdl.handle.net/1866/20880

Evidence of a unique and common genetic etiology between the CAR and the remaining part of the diurnal cycle : a study of 14 year-old twins

Article [Accepted Manuscript]
Thumbnail
Ouellet-Morin_2016_id_5562.pdf (795.2Kb)
Is part of
Psychoneuroendocrinology ; vol. 66, p. 91-100
Publisher(s)
Elsevier
2016-04
Author(s)
Ouellet-Morin, Isabelle
Brendgen, Mara
Girard, Alain
Dionne, Ginette
Lupien, Sonia
Vitaro, Frank
Boivin, Michel
Affiliation
  • Université de Montréal. Faculté des arts et des sciences. École de criminologie
  • Université de Montréal. Faculté des arts et des sciences. École de psychoéducation
Keywords
  • HPA axis
  • Cortisol
  • Diurnal rhythm
  • Genes
  • Twin studies
  • Cortisol awakening response
Abstract(s)
Introduction By and large, studies have reported moderate contributions of genetic factors to cortisol secreted in the early morning and even smaller estimates later in the day. In contrast, the cortisol awakening response (CAR) has shown much stronger heritability estimates, which prompted the hypothesis that the etiology of cortisol secretion may vary according to the time of day. A direct test of this possibility has, however, not yet been performed. Objective To describe the specific and common etiology of the CAR, awakening level and cortisol change from morning to evening in an age-homogenous sample of twin adolescents. Methods A total of 592 participants of the Québec Newborn Twin Study, a population-based 1995–1998 cohort of families with twins in Canada, have collected saliva at awakening, 30 min later, at the end of afternoon and in the evening over four collection days. Results Multivariate Cholesky models showed both specific and common sources of variance between the CAR, awakening and cortisol diurnal change. The CAR had the strongest heritability estimates, which, for the most part, did not overlap with the other indicators. Conversely, similar magnitudes of genetic and environmental contributions were detected at awakening and for diurnal change, which partially overlapped. Conclusion Our study unraveled differences between the latent etiologies of the CAR and the rest of the diurnal cycle, which may contribute to identify regulatory genes and environments and detangle how these indicators each relate to physical and mental health.
Other location(s)
https://doi.org/10.1016/j.psyneuen.2015.12.022
Collections
  • FAS – École de psychoéducation – Travaux et publications [110]

DSpace software [version 5.8 XMLUI], copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback
Certificat SSL / SSL Certificate
les bibliothéques/UdeM
  • Emergency
  • Private life
  • Careers
  • My email
  • StudiUM
  • iTunes U
  • Contact us
  • Facebook
  • YouTube
  • Twitter
  • University RSS
 

 


DSpace software [version 5.8 XMLUI], copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback
Certificat SSL / SSL Certificate
les bibliothéques/UdeM
  • Emergency
  • Private life
  • Careers
  • My email
  • StudiUM
  • iTunes U
  • Contact us
  • Facebook
  • YouTube
  • Twitter
  • University RSS