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  • Role of manganese in the pathogenesis of portal-systemic encephalopathy 

    Pomier-Layrargues, Gilles; Rose, Christopher F.; Spahr, Laurent; Zayed, Joseph; Normandin, Louise; Butterworth, Roger F. (1998-12)
    Amongst the potential neurotoxins implicated in the pathogenesis of hepatic encephalopathy, manganese emerges as a new candidate. In patients with chronic liver diseases, manganese accumulates in blood and brain leading to pallidal signal hyperintensity ...