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  • Increased brain lactate is central to the development of brain edema in rats with chronic liver disease 

    Bosoi, Cristina R.; Zwingmann, Claudia; Marin, Helen A.; Parent-Robitaille, Christian; Huynh, Jimmy; Tremblay, Mélanie; Rose, Christopher F. (2014)
    The pathogenesis of brain edema in patients with chronic liver disease (CLD) and minimal hepatic encephalopathy (HE) remains undefined. This study evaluated the role of brain lactate, glutamine and organic osmolytes, including myo-inositol and taurine, ...