Now showing items 21-40 of 386

  • Distinct cognitive and discriminative stimulus effects of ketamine enantiomers in rats 

    Popik, Piotr; Khoo, Shaun Yon-Seng; Kuziak, Agata; Golebiowska, Joanna; Potasiewicz, Agnieszka; Hogendorf, Adam; Popik, Oskar; Matloka, Mikolaj; Moszczynski, Rafal; Nikiforuk, Agnieszka; Witkin, Jeffrey M. (Elsevier, 2020-08-03)
    Although (S)-ketamine was approved for use in treatment-resistant depression in 2019, new preclinical findings suggest that (R)-ketamine might produce better efficacy and tolerability relative to (S)-ketamine. Here we evaluated the effects of (R)-, ...
  • Electroencephalographic markers of idiopathic hypersomnia : where we are and where we are going 

    Deshaies-Rugama, Anne-Sophie; Desautels, Alex; Montplaisir, Jacques-Yves; Carrier, Julie; Thompson, Cynthia; Blais, Hélène; Lina, Jean-Marc; Gosselin, Nadia (Springer, 2020-07-27)
    Purpose of the review: Idiopathic hypersomnia is a poorly defined nosological entity and has important phenotype heterogeneity. Moreover, diagnosing idiopathic hypersomnia is challenging as patients can report significant symptoms but may not meet ...
  • Inclusion of relatives in stroke rehabilitation : Perception of quality of services they received in the context of early supported discharged (ESD), in- and out-patient services 

    Quality of stroke rehabilitation services to relatives
    Rochette, Annie; Dugas, Ariane; Morissette-Gravel, Anne-Sophie (Taylor and Francis, 2020-07-11)
    Background Relatives of stroke patients should be an integral part of the continuum of rehabilitation services. Objective The objective was to describe their perception of the quality of the services they received in the context of early supported ...
  • Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats 

    Khazoom, François; L'Écuyer, Sydnée; Gilbert, Kim; Gagné, Marc-André; Bouchard, Caroline; Rose, Christopher; Rousseau, Guy; Charbonney, Emmanuel (Lippincott, Williams & Wilkins, 2020-07-06)
    BACKGROUND Multiorgan failure is a consequence of severe ischemia-reperfusion injury after traumatic hemorrhagic shock (HS), a major cause of mortality in trauma patients. Circulating uric acid (UA), released from cell lysis, is known to activate ...
  • Acute carotid stenting in patients undergoing thrombectomy : a systematic review and meta-analysis 

    Dufort, Gabrielle; Chen, Bing Yu; Jacquin, Grégory; Keezer, Mark; Labrie, Marilyn; Rioux, Bastien; Stapf, Christian; Ziegler, Daniela; Y Poppe, Alexandre (BMJ Publishing Group, 2020-06-12)
    Background The benefit of acute carotid stenting compared with no acute stenting on clinical outcomes among patients with tandem lesions (TL) undergoing endovascular thrombectomy (EVT) remains unknown. Methods We conducted a a systematic review and ...
  • Negative emotions during exercise may induce specific ventilatory patterns 

    Gruet, Mathieu; Romain, Ahmed Jérôme; Pageaux, Benjamin (American Physiological Society, 2020-05-15)
  • Expressive and receptive use of speech and graphic symbols by typically developing children: What skills contribute to performance on structured sentence-level tasks? 

    Expressive and receptive use of graphic symbols
    Sutton, Ann; Trudeau, Natacha; Morford, Jill P.; Smith, Martine M. (Taylor and Francis, 2020-05-04)
    Purpose: To explore expressive and receptive use of speech and graphic symbols and relationships with linguistic and cognitive skills in children with typical development. Method: Participants were 82 children with typical development (4 to 9 years). ...
  • Elevated serum liver-type fatty acid binding protein levels in non-acetaminophen acute liver failure patients with organ dysfunction. 

    Karvellas, Constantine J.; Speiser, Jaime L.; Tremblay, Mélanie; Lee, William M.; Rose, Christopher (Springer, 2020-03-03)
    Liver-type fatty acid binding protein (FABP1) has previously been demonstrated to improve prognostic discrimination in acetaminophen (APAP)-induced ALF but has not been investigated in other etiologies of ALF. AIM: To determine ...
  • Predicting early post-stroke aphasia outcome from initial aphasia severity 

    Osa Garcia, Alberto; Brambati, Simona Maria; Brisebois, Amélie; Désilets-Barnabé, Marianne; Bedetti, Christophe; Rochon, Elizabeth; Leonard, Carol; Desautels, Alex; Leonard, Carol; Marcotte, Karine (Frontiers media, 2020-02-21)
    Background: The greatest degree of language recovery in post-stroke aphasia takes place within the first weeks. Aphasia severity and lesion measures have been shown to be good predictors of long-term outcomes. However, little is known about their ...
  • Long-term discourse outcomes and their relationship to white matter damage in moderate to severe adulthood traumatic brain injury 

    Marcotte, Karine; Sanchez, Erlan; Arbour, Caroline; Brambati, Simona Maria; Bedetti, Christophe; Martineau, Sarah; Descoteaux, Maxime; Gosselin, Nadia (Elsevier, 2020-02-17)
  • Autophagy drives fibroblast senescence through MTORC2 regulation 

    Autophagy, senescence and myofibroblast differentiation
    Bernard, Monique; Yang, Bing; Migneault, Francis; Turgeon, Julie; Dieudé, Mélanie; Olivier, Marc-Alexandre; Cardin, Guillaume B.; El-Diwany, Mostafa; Underwood, Katy; Rodier, Francis; Hébert, Marie-Josée (Taylor & Francis, 2020-01-13)
    Sustained macroautophagy/autophagy favors the differentiation of fibroblasts into myofibroblasts. Cellular senescence, another means of responding to long-term cellular stress, has also been linked to myofibroblast differentiation and fibrosis. Here, ...
  • Analysis of common and rare VPS13C variants in late-onset Parkinson disease 

    Rudakou, Uladzislau; Ruskey, Jennifer A.; Krohn, Lynne; Laurent, Sandra B.; Spiegelman, Dan; Greenbaum, Lior; Yahalom, Gilad; Desautels, Alex; Montplaisir, Jacques-Yves; Fahn, Stanley; Waters, Cheryl; Levy, Oren; Kehoe, Caitlin M.; Narayan, Sushma; Dauvilliers, Yves; Dupré, Nicolas; Hassin-Baer, Sharon; Alcalay, Roy N.; Rouleau, Guy; Fon, Edward A.; Gan-Or, Ziv (Lippincott, Williams and Wilkins, 2020-01-09)
    Objective We aimed to study the role of coding VPS13C variants in a large cohort of patients with lateonset Parkinson disease (PD) (LOPD). Methods VPS13C and its untranslated regions were sequenced using targeted next-generation sequencing in 1,567 ...
  • A pilot study on the Mirror Effect PLUS protocol : a standardized and adapted facial rehabilitation for acute Bell’s palsy 

    = Post lengthening temporalis myoplasty facial rehabilitation by speech-language pathologists : a study of three patients
    Mirror effect PLUS protocol for acute Bell’s palsy
    Martineau, Sarah; Martel-Sauvageau, Vincent; Piette, Éric; Rahal, Akram; Chouinard, Anne-Marie; Marcotte, Karine (Canadian association of speech-language pathologists and audiologists, 2020-01)
    Combining early facial exercises with medication may help patients with acute Bell’s palsy recover significantly faster and better than patients treated with medication alone. To date, exercise therapy in acute Bell’s palsy consists mostly of ...
  • The importance of thematic informativeness in narrative discourse recovery in acute post-stroke aphasia 

    Brisebois, Amélie; Brambati, Simona Maria; Désilets-Barnabé, Marianne; Boucher, Johémie; Osa García, Alberto; Rochon, Elizabeth; Leonard, Carol; Desautels, Alex; Marcotte, Karine (Routledge, 2019-12-24)
    Background: Discourse analysis allows the examination of functional and ecological language impairment in post-stroke aphasia. Given its complexity, various methods of analysis have been developed to measure the multiple components of discourse. Clinical ...
  • HIV-1 envelope glycoprotein amino acids signatures associated with clade B transmitted/founder and recent viruses 

    Kafando, Alexis; Martineau, Christine; El-Far, Mohamed; Fournier, Eric; Doualla-Bell, Florence; Serhir, Bouchra; Kazienga, Adama; Sangaré, Mohamed Ndongo; Sylla, Mohamed; Chamberland, Annie; Charest, Hugues; Tremblay, Cécile (MDPI, 2019-11-01)
    Background: HIV-1 transmitted/founder viruses (TF) are selected during the acute phase of infection from a multitude of virions present during transmission. They possess the capacity to establish infection and viral dissemination in a new host. Deciphering ...
  • Perceived needs and difficulties in meal preparation ofpeople living with traumatic brain injury in a chronicphase : supporting long-term services and interventions 

    Dubuc, Érika; Gagnon-Roy, Mireille; Couture, Mélanie; Bier, Nathalie; Giroux, Sylvain; Bottari, Carolina (Wiley, 2019-10-08)
    Introduction: Traumatic brain injury (TBI) is a chronic medical condition with life-long consequences. Meal preparation is one the most significant activities impacted by TBI even after more than 10 years post-trauma. However, substantial gaps exist ...
  • The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis 

    Mouchiroud, Mathilde; Camiré, Étienne; Aldow, Manal; Caron, Alexandre; Jubinville, Éric; Turcotte, Laurie; Kaci, Inés; Beaulieu, Marie-Josée; Roy, Christian; Labbé, Sébastien M.; Varin, Thibault V.; Gélinas, Yves; Lamothe, Jennifer; Trottier, Jocelyn; Mitchell, Patricia L.; Guénard, Frédéric; Festuccia, William T.; Joubert, Philippe; Rose, Christopher; Karvellas, Constantine J.; Barbier, Olivier; Morissette, Mathieu C.; Marette, André; Laplante, Mathieu (Elsevier, 2019-10-04)
    Objectives Hepatokines are proteins secreted by the liver that impact the functions of the liver and various tissues through autocrine, paracrine, and endocrine signaling. Recently, Tsukushi (TSK) was identified as a new hepatokine that is induced by ...
  • A short-term assessment of nascent HIV-1 transmission clusters among newly diagnosed individuals using envelope sequence-based phylogenetic analyses 

    Kafando, Alexis; Serhir, Bouchra; Doualla-Bell, Florence; Fournier, Eric; Sangaré, Mohamed Ndongo; Martineau, Christine; Sylla, Mohamed; Chamberland, Annie; El-Far, Mohamed; Charest, Hugues; Tremblay, Cécile (Mary Ann Liebert, 2019-10-01)
    The identification of transmission clusters (TCs) of HIV-1 using phylogenetic analyses can provide insights into viral transmission network and help improve prevention strategies. We compared the use of partial HIV-1 envelope fragment of 1,070 bp ...
  • Le trouble développemental du langage (TDL) : mise à jour interdisciplinaire 

    Breault, Chantale; Béliveau, Marie-Julie; Labelle, Fannie; Valade, Florence; Trudeau, Natacha (2019-07-17)
    Bien que le trouble développemental du langage (TDL) soit fréquent (7,58 %; Norbury et al., 2016) et ait des impacts perdurant jusqu’à l’âge adulte (Feeney, Desha, Khan, Ziviani, & Nicholson, 2016), il est beaucoup moins connu que d’autres problématiques ...
  • Perceptions of emergency medicine residents of multisource feedback : different, relevant, and useful information 

    Castonguay, Véronique; Lavoie, Patrick; Karazivan, Philippe; Morris, Judy; Gagnon, Robert (Elsevier, 2019-07-04)
    Objective Multisource feedback is a process through which different members of the care team assess and provide feedback on residents’ competencies, usually those that are less often addressed by traditional assessment methods (i.e., communication, ...