Browsing Faculté de médecine – Travaux et publications by Title
Now showing items 1-55 of 714
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A 12-week open-label, multicenter study evaluating the safety and patient-reported efficacy of sodium oxybate in patients with narcolepsy and cataplexy
(Elsevier, 2015)Objective: This study aimed to evaluate safety and efficacy of sodium oxybate (SXB) titrated to effect. Methods: SXB-naive patients who had participated in a randomized SXB clinical trial and had not been titrated to adequate clinical effect were ... -
175 years of bilirubin testing : ready for point-of-care?
(Wiley, 2023-04-10)Bilirubin was first detected in blood in 1847 and since then has become one of the most widely used biomarkers for liver disease. Clinical routine bilirubin testing is performed at the hospital laboratory, and the gold standard colorimetric test is ... -
2021 ISHEN guidelines on animal models of hepatic encephalopathy
(Wiley, 2021-04-01)This working group of the International Society of Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) was commissioned to summarize and update current efforts in the development and characterization of animal models of hepatic encephalopathy (HE). ... -
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection
(American Association for the Advancement of Science, 2015-12-16)Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ transplant recipients. However, mechanisms of immunization to apoptotic components remain largely uncharacterized. We used large-scale ... -
3D Cohort Study : The Integrated Research Network in Perinatology of Quebec and Eastern Ontario
(Wiley, 2016)Background: The 3D Cohort Study (Design, Develop, Discover) was established to help bridge knowledge gaps about the links between various adverse exposures during pregnancy with birth outcomes and later health outcomes in children. Methods: Pregnant ... -
3D registration of MR and X-ray spine images using an articulated model
(2012-07)Présentation: Cet article a été publié dans le journal : Computerised medical imaging and graphics (CMIG). Le but de cet article est de recaler les vertèbres extraites à partir d’images RM avec des vertèbres extraites à partir d’images RX pour des ... -
The 3D-Transition study : objectives, methods, and implementation of an innovative planned missing data design
(Oxford University Press, 2021-05-12)The prevalence of mental health problems represents a significant burden on school and community health resources as early as preschool. Reducing this burden requires a better understanding of the developmental mechanisms linking children’s early ... -
Abdominal motion tracking with free-breathing XD-GRASP acquisitions using spatio-temporal geodesic trajectories
Correction to: Abdominal motion tracking with free‑breathing XD‑GRASP acquisitions using spatio‑temporal geodesic trajectories
(Springer, 2022-01-14)Free-breathing external beam radiotherapy remains challenging due to the complex elastic or irregular motion of abdominal organs, as imaging moving organs leads to the creation of motion blurring artifacts. In this paper, we propose a radial-based MRI ... -
Abstracts of posters and platform sessions accepted for virtual presentation at the 2020 Annual Meeting of the Society for developmental and behavioral pediatrics. Pubertal development and adolescent alcohol use : a prospective study on the role of sensation seeking and impulsivity. Abstract 46
(Lippincott, Williams & Wilkins, 2021-02-01) -
L'accord de l'adjectif chez les enfants francophones avec un trouble spécifique du langage
Adjective concord in Young French-speakers with specific language impairment
La concordancia adjetival en franco hablantes con trastorno especifico del lenguaje(École d'orthophonie et d'audiologie, 2010)En dépit du fait que l’étude de la production du syntagme nominal puisse fournir des données riches sur les phénomènes d’accord et de concordance, cette structure demeure peu étudiée. L’étude rapportée ici décrit l’accord intra-nominal, - c’est-à-dire ... -
L’acquisition du genre quand il est déjà acquis : l’expérience d’enfants hispanophones apprenant le français
The acquisition of gender once it has already been mastered: The experience of Spanish-speaking children learning French
(Orthophonie et Audiologie Canada, 2015)This study tests the acquisition of French in Spanish-speaking children by documenting the acquisition of noun phrases in sequential bilingual (Spanish-French) children, compared to native French speakers, matched according to age or language development ... -
Acquisition of French adjectives in Quebec French as revealed by elicitation data
Acquisition of Quebec French adjectives as revealed by elicitation data
(Cambridge University Press, 2010)This study presents data from an elicitation study on French size and color adjectives in noun phrases (DPs), both early acquired structures. Thirty-two francophone children aged 3–5 years participated in the study. Adjectives were elicited using ... -
Active nuclear import and cytoplasmic retention of activation-induced deaminase
(2009)The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms ... -
Activity monitor placed at the non-paretic ankle is accurate in measuring step counts during community walking in post-stroke individuals : a validation study
(Wiley, 2019-01-28)Background: Different environmental factors may affect the accuracy of step-count activity monitors (AM). However, the validationconditions for AM accuracy largely differ from ecological environments.Objectives: To assess and compare the accuracy of ... -
Acute carotid stenting in patients undergoing thrombectomy : a systematic review and meta-analysis
(BMJ Publishing Group, 2020-06-12)Background The benefit of acute carotid stenting compared with no acute stenting on clinical outcomes among patients with tandem lesions (TL) undergoing endovascular thrombectomy (EVT) remains unknown. Methods We conducted a a systematic review and ... -
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH
(2005)Hyperammonemia is a key factor in the pathogenesis of hepatic encephalopathy (HE) as well as other metabolic encephalopathies, such as those associated with inherited disorders of urea cycle enzymes and in Reye's syndrome. Acute HE results in increased ... -
Acute invariant NKT cell activation triggers an immune response that drives prominent changes in iron homeostasis
(Nature research, 2020-12-03)Iron homeostasis is an essential biological process that ensures the tissue distribution of iron for various cellular processes. As the major producer of hepcidin, the liver is central to the regulation of iron metabolism. The liver is also home to ... -
Adaptation and reliability of the Cinderella story retell task in Canadian French persons without brain injury
(American Speech-Language-Hearing Association, 2023-09-27)Purpose: Main concept (MC) analysis is a well-documented method of discourse analysis in adults with and without brain injury. This study aims to develop a MC checklist that is culturally and linguistically adapted for Canadian French speakers and ... -
The added value of quantitative ultrasound to shear-wave elastography for assessment of steatohepatitis in a rat model
(Institute of electrical and electronics engineers, 2019-12-08)Non-alcoholic fatty liver disease is a highly prevalent condition, which may progress to non-alcoholic steatohepatitis (NASH), an advanced form found in 3 to 5% of the population. As liver biopsy is invasive, there is a need for a non-invasive technique ... -
Addition of exogenous polypeptides on the mammalian reovirus outer capsid using reverse genetics
(Elsevier, 2012-02)Addition of exogenous peptide sequences on viral capsids is a powerful approach to study the process of viral infection or to retarget viruses toward defined cell types. Until recently, it was not possible to manipulate the genome of mammalian reovirus ... -
Adhesion and transcellular migration of neutrophils and B lymphocytes on fibroblasts
(2009)During tissue inflammation, infiltrated leukocytes may have physical contacts with fibroblasts. We observed that neutrophils and B lymphocytes adhered in a larger proportion than T cells on cultured fibroblasts. Microscopy showed that adhesion was also ... -
Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight
(Elsevier, 2016-08-23)Objective We previously demonstrated that the handle-region peptide, a prorenin/renin receptor [(P)RR] blocker, reduces body weight and fat mass and may improve insulin sensitivity in high-fat fed mice. We hypothesized that knocking out the adipose ... -
Adiposity and cardiac autonomic function in children with a family history of obesity
(Springer, 2024-09-21)Purpose Data on associations between adiposity and heart rate variability (HRV) in pre-pubertal children are limited. We examined the associations between adiposity indices and HRV, independent of lifestyle behaviors, comparing multiple indicators ... -
The adoption of LI-RADS : a survey of non-academic radiologists
(Springer, 2023-05-26)Purpose: To understand the practice and determinants of non-academic radiologists regarding LIRADS and the four current LI-RADS algorithms: CT/MRI, contrast-enhanced ultrasound (CEUS), ultrasound (US), and CT/MRI Treatment Response. Materials and ... -
Advancing social inclusion of people with disabilities through awareness and training activities : a collaborative process between community partners and researchers
(Elsevier, 2021-05-23)Objective The main objectives were to 1) search and map current disability awareness and training activities in Quebec, Canada, 2) collectively reflect on these practices, and 3) develop a five-year strategic plan. Methods We used an integrated ... -
Albumin dialysis : a new therapeutic strategy for intoxication from protein-bound drugs
(Springer, 2004-01-21)Abstract Objective: Although water-soluble drugs can be removed by haemofiltration/haemodialysis, morbidity and mortality from intoxication with protein-bound drugs remains high. The present study investigates whether albumin dialysis in the form of ... -
Algal Biofuels: Challenges and Opportunities
(Elsevier, 2013)Biodiesel production using microalgae is attractive in a number of respects. Here a number of pros and cons to using microalgae for biofuels production are reviewed. Algal cultivation can be carried out using non-arable land and non-potable water with ... -
Altered sensory-weighting mechanisms is observed in adolescents with idiopathic scoliosis
(2006)BACKGROUND:Scoliosis is the most common type of spinal deformity. In North American children, adolescent idiopathic scoliosis (AIS) makes up about 90% of all cases of scoliosis. While its prevalence is about 2% to 3% in children aged between 10 to 16 ... -
Alternative Time Representation in Dopamine Models
(Springer Science + Business Media, 2009)Données originales publiées dans l'article: Rivest, F, Kalaska, J.F., Bengio, Y. (2009) Alternative time representation in dopamine models. Journal of Computational Neuroscience. doi:10.1007/s10827-009-0191-1 -
Amino acid substitutions in σ1 and μ1 outer capsid proteins are selected during mammalian reovirus adaptation to Vero cells
(Elsevier, 2013-09)Establishment of viral persistence in cell culture has previously led to the selection of mammalian reovirus mutants, although very few of those have been characterized in details. In the present study, reovirus was adapted to Vero cells that, in ... -
Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly
(Elsevier, 2015-01-01)In a recent study, the serotype 3 Dearing strain of mammalian orthoreovirus was adapted to Vero cells; cells that exhibit a limited ability to support the early steps of reovirus uncoating and are unable to produce interferon as an antiviral response ... -
Amino acids, ammonia, and hepatic encephalopathy
(Elsevier, 2022-04-30)Hepatic encephalopathy (HE) is a decline in brain function arising due to liver insufficiency. The liver's diminished capacity to clear ammonia, and the subsequent accumulation of it, is highly implicated in pathogenesis of HE. Ammonia is endogenously ... -
Ammonia : this is not the end but rather the end of the beginning
(Elsevier, 2018-04)Hepatic encephalopathy (HE) represents a wide spectrum of neurological or neuropsychological symptoms caused by liver disease and/or portosystemic shunts. The major role of hyperammonemia in association with systemic inflammation and oxidative stress ... -
Ammonia toxicity: from head to toe?
(Springer, 2016-12)Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues. It is known that the toxic ramifications of ammonia primarily touch the brain and cause ... -
Ammonia: more than a neurotoxin?
(2014) -
Ammonia‐lowering strategies for the treatment of hepatic encephalopathy
(Wiley, 2012-08-08)Hyperammonemia leads to neurotoxic levels of brain ammonia and is a major factor involved in the pathogenesis of hepatic encephalopathy (HE). Ammonia‐lowering treatments primarily involve two strategies: inhibiting ammonia production and/or increasing ... -
AnaBench: a Web/CORBA-based workbench for biomolecular sequence analysis
(2003)BACKGROUND:Sequence data analyses such as gene identification, structure modeling or phylogenetic tree inference involve a variety of bioinformatics software tools. Due to the heterogeneity of bioinformatics tools in usage and data requirements, ... -
Analysis of common and rare VPS13C variants in late-onset Parkinson disease
(Lippincott, Williams and Wilkins, 2020-01-09)Objective We aimed to study the role of coding VPS13C variants in a large cohort of patients with lateonset Parkinson disease (PD) (LOPD). Methods VPS13C and its untranslated regions were sequenced using targeted next-generation sequencing in 1,567 ... -
Analysis of electrocardiograms during atrial fibrillation
(Institute of electrical and electronics engineers, 2006-11-30)The research discussed in this article is motivated by the search for an optimal classification of the different types of atrial fibrillation (AF) on the basis of recorded atrial signals. This would facilitate the selection of an optimal therapy. This ... -
Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae
(2004)BACKGROUND:The HIV-1 genome encodes a well-conserved accessory gene product, Vpr, that serves multiple functions in the retroviral life cycle, including the enhancement of viral replication in nondividing macrophages, the induction of G2 cell-cycle ... -
Analysis of scoliosis trunk deformities using ICA
(2012-07-02)This paper describes a method for analyzing scoliosis trunk deformities using Independent Component Analysis (ICA). Our hypothesis is that ICA can capture the scoliosis deformities visible on the trunk. Unlike Principal Component Analysis (PCA), ICA ... -
Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment
(2010)The Vpu accessory protein promotes HIV-1 release by counteracting Tetherin/BST-2, an interferon-regulated restriction factor, which retains virions at the cell-surface. Recent reports proposed beta-TrCP-dependent proteasomal and/or endo-lysosomal ... -
Anti-pronator components are essential to effectively alter lower-limb kinematics and kinetics in individuals with flexible flatfeet
(Elsevier, 2021-05-23)Background Foot orthoses are commonly used to correct for foot alterations and especially address excessive foot pronation in individuals with flatfeet. In recent years, 3D printing has taken a key place in orthotic manufacturing processes as it offers ... -
Anxiety, mood disorders and injection risk behaviors among cocaine users: results from the COSMO study
(Wiley, 2015-10)Background and Objectives: Despite being common among cocaine users, mental health problems and their relationship with HIV and hepatitis C high risk injection behaviors are poorly documented. This study was undertaken to examine the relationships ... -
Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis
(Springer Nature, 2023-07-20)Apoptosis of endothelial cells prompts the release of apoptotic exosome-like vesicles (ApoExos), subtype extracellular vesicles secreted by apoptotic cells after caspase-3 activation. ApoExos are different from both apoptotic bodies and classical ... -
Application of a new method in the study of pelvic floor muscle passive properties in continent women
(2010-10)The aim of this study was to present a new methodology for evaluating the pelvic floor muscle (PFM) passive properties. The properties were assessed in 13 continent women using an intra-vaginal dynamometric speculum and EMG (to ensure the subjects were ... -
Are athletes psychologically ready for sport following a concussion?
(BMJ publishing group, 2017-12-18) -
Are hypopressive and other exercise programs efective for the treatment of pelvic organ prolapse?
(Springer, 2022-11-23)Introduction and hypothesis Pelvic floor muscle training (PFMT) is effective for the treatment of pelvic organ prolapse (POP), but other exercise programs have also been promoted and used. The aim of this review was to evaluate the effect of hypopressive ... -
Are second language learners just as good at verb morphology as first language learners?
(Boston University Conference on Language Development, 2015)We addressed whether children learning French as a first (L1) and multilingual children (MUL, for whom French is a second or third language) are sensitive to sub-regular verb conjugation patterns (i.e., neither default, nor idiosyncratic) (e.g., Albright, ... -
Are stress and mixed urinary incontinence associated with impaired executive control in community-dwelling older women?
(2013-05)Objectives: To assess whether stress or mixed urinary incontinence (UI) is associated with deficits in executive functioning among community-dwelling women. Design: An observational study comparing the performance, using multivariate analyses of variance ... -
Article processing charge hyperinflation and price insensitivity : an open access sequel to the serials crisis
(LIBER, 2019)Open access publishing has frequently been proposed as a solution to the serials crisis, which involved unsustainable budgetary pressures on libraries due to hyperinflation of subscription costs. The majority of open access articles are published in ... -
Articulated Model Registration of MRI/X-Ray Spine Data
(Springer Berlin Heidelberg, 2010-06)This paper presents a method based on articulated models for the registration of spine data extracted from multimodal medical images of patients with scoliosis. With the ultimate aim being the development of a complete geometrical model of the torso ... -
Assessment methods in sexual rehabilitation after stroke : a scoping review for rehabilitation professionals
(Taylor and Francis, 2021-03-09)Purpose: The aim was to identify and describe the assessment methods used by rehabilitation professionals to evaluate sexuality for individuals post-stroke, as well as the domains of sexuality addressed. Methods: Seven databases were selected for ... -
Assessment of involuntary PFM contractions in comparison with existing literature and IUGA/ICS terminology reports
(Springer, 2024-02-08)Introduction and Hypothesis Involuntary pelvic floor muscle (PFM) contractions are thought to occur during an increase in intra-abdominal pressure (IAP). Although no studies have assessed their presence in women with normal pelvic floor (PF) function, ... -
Assessment of left ventricular diastolic function by transesophageal echocardiography before cardiopulmonary bypass : clinical implications of a restrictive profile
(Elsevier, 2019-05-16)Objective Left ventricular (LV) diastolic function can be assessed by transesophageal echocardiography before cardiopulmonary bypass in the setting of cardiac surgery. The objective of this study was to determine whether the assessment of LV diastolic ...
