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Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults
Gray matter increases with obstructive sleep apnea
(American Thoracic Society, 2017-06-01)
Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations,
and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly
assessed with neuroimaging.
Objectives: ...
Sleep slow waves’ negative-to-positive-phase transition : a marker of cognitive and apneic status in aging
(Oxford University Press, 2022-10-11)
The sleep slow-wave (SW) transition between negative and positive phases is thought to mirror synaptic strength and likely depends
on brain health. This transition shows signifcant age-related changes but has not been ...
Effects of menopause on sleep quality and sleep disorders : Canadian longitudinal study on aging
(Lippincott, Williams & Wilkins, 2020-02-29)
OBJECTIVES:Sleep complaints are common during the menopause transition. However, it is difficult to disentangle changes in sleep related to aging from those directly due to menopause. We compared sleep disorders in 45 to ...
Are age and sex effects on sleep slow waves only a matter of EEG amplitude ?
(Oxford University Press, 2020-09-15)
Aging is associated with reduced slow wave (SW) density (number SW/min in nonrapid-eye movement sleep) and amplitude.
It has been proposed that an age-related decrease in SW density may be due to a reduction in ...
Sleep spindles are resilient to extensive white matter deterioration
(Oxford University Press, 2020-06-13)
Sleep spindles are an essential part of non-rapid eye movement sleep, notably involved in sleep consolidation, cognition, learning
and memory. These oscillatory waves depend on an interaction loop between the thalamus and ...
Cerebral white matter diffusion properties and free‐water with obstructive sleep apnea severity in older adults
(Wiley, 2020-03-13)
Characterizing the effects of obstructive sleep apnea (OSA) on the aging brain could be key in our understanding of neurodegeneration in this population. Our objective was to assess white matter properties in newly diagnosed ...
EEG connectivity across sleep cycles and age
(American academy of sleep medicine, 2019-11-06)
Study Objectives
In young adults, sleep is associated with important changes in cerebral connectivity during the first cycle of non-rapid eye movement (NREM) sleep. Our study aimed to evaluate how electroencephalography ...
Obstructive sleep apnea and the risk of cognitive decline in older adults
(American Thoracic Society, 2019-01-15)
Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure ...
Brain white matter damage and its association with neuronal synchrony during sleep
(Oxford University Press, 2019-01-28)
The restorative function of sleep partly relies on its ability to deeply synchronize cerebral networks to create large slow oscillations observable with EEG. However, whether a brain can properly synchronize and produce a ...
Aging reduces the stimulating effect of blue light on cognitive brain functions
(Oxford University Press, 2014-01-01)
Study Objectives:
Light exposure, particularly blue light, is being recognized as a potent mean to stimulate alertness and cognition in young individuals. Aging is associated with changes in alertness regulation and ...