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Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults
Gray matter increases with obstructive sleep apnea
(American Thoracic Society, 2017-06-01)
Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations,
and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly
assessed with neuroimaging.
Objectives: ...
Sleep spindles are resilient to extensive white matter deterioration
(Oxford University Press, 2020-06-13)
Sleep spindles are an essential part of non-rapid eye movement sleep, notably involved in sleep consolidation, cognition, learning
and memory. These oscillatory waves depend on an interaction loop between the thalamus and ...
Obstructive sleep apnea and the risk of cognitive decline in older adults
(American Thoracic Society, 2019-01-15)
Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure ...
Brain white matter damage and its association with neuronal synchrony during sleep
(Oxford University Press, 2019-01-28)
The restorative function of sleep partly relies on its ability to deeply synchronize cerebral networks to create large slow oscillations observable with EEG. However, whether a brain can properly synchronize and produce a ...
Obstructive sleep apnea during REM sleep and daytime cerebral functioning : a regional cerebral blood flow study using high-resolution SPECT
(SAGE, 2018-11-22)
Obstructive sleep apnea (OSA) predominantly during rapid eye movement (REM) sleep may have impacts on brain health, even in milder OSA cases. Here, we evaluated whether REM sleep OSA is associated with abnormal daytime ...
Biomarkers of dementia in obstructive sleep apnea
(Elsevier, 2018-08-13)
Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep
apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due
to obstructive ...